Emerging 2019 Novel Coronavirus (2019-nCoV) Pneumonia

Song, Fengxiang; Shi, Nannan; Shan, Fei; Zhang, Zhiyong; Shen, Jie; Lu, Hongzhou; Ling, Yun; Jiang, Yanyun; Shi, Yuxin

doi:10.1148/radiol.2020200274

Cited by 1,211 publications

(1,250 citation statements)

References 12 publications

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“…In contrast, no discrete nodules, cavitation, pleural effusion or lymphadenopathy were observed on the chest CT images [33 , 34] . Another study including 51 cases showed similar findings [35] : most CT images showed pure GGO (77%), followed by GGO with reticular and/or interlobular septal thickening (75%), GGO with consolidation (59%) and pure consolidation (55%). Of the 51 cases, 86% showed bilateral lung involvement, and the above findings were peripherally distributed in 86% of cases [35] .…”

Section: Imagingsupporting

confidence: 62%

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges

Lai

Shih

et al. 2020

International Journal of Antimicrobial Agents

5,305

4,340

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Section: Imagingsupporting

confidence: 62%

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges

Lai

Shih

et al. 2020

International Journal of Antimicrobial Agents

5,305

4,340

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“…19 , 20 The patterns of GGOs or GGO with the above features in predominantly peripheral distribution will facilitate the diagnosis of COVID-19 pneumonia. 20 The above imaging findings could be mostly explained by a recently published research on the pathological investigation of COVID-19. 25 Diffuse alveolar injury superimposed with cellular fibromyxoid exudates and hyaline membrane formation was identified on pathology.…”

Section: Discussionmentioning

confidence: 95%

“…Regarding the number of lesions, the lesion was counted as the involved lung segments if a lesion extends across multiple lung segments. 20 Lymphadenopathy was defined as the size of lymph node more than 10 mm in short-axis diameter.…”

Section: Image Interpretationmentioning

confidence: 99%

Clinical and CT imaging features of the COVID-19 pneumonia: Focus on pregnant women and children

Liu¹,

Liu²,

Li³

et al. 2020

Journal of Infection

376

213

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s u m m a r yBackground: The ongoing outbreak of COVID-19 pneumonia is globally concerning. We aimed to investigate the clinical and CT features in the pregnant women and children with this disease, which have not been well reported. Methods: Clinical and CT data of 59 patients with COVID-19 from January 27 to February 14, 2020 were retrospectively reviewed, including 14 laboratory-confirmed non-pregnant adults, 16 laboratory-confirmed and 25 clinically-diagnosed pregnant women, and 4 laboratory-confirmed children. The clinical and CT features were analyzed and compared. Findings: Compared with the non-pregnant adults group ( n = 14), initial normal body temperature (9 [56%] and 16 [64%]), leukocytosis (8 [50%] and 9 [36%]) and elevated neutrophil ratio (14 [88%] and 20 [80%]), and lymphopenia (9 [56%] and 16 [64%]) were more common in the laboratory-confirmed ( n = 16) and clinically-diagnosed ( n = 25) pregnant groups. Totally 614 lesions were detected with predominantly peripheral and bilateral distributions in 54 (98%) and 37 (67%) patients, respectively. Pure ground-glass opacity (GGO) was the predominant presence in 94/131 (72%) lesions for the non-pregnant adults. Mixed consolidation and complete consolidation were more common in the laboratory-confirmed (70/161 [43%]) and clinically-diagnosed (153/322 [48%]) pregnant groups than 37/131 (28%) in the non-pregnant adults ( P = 0 ·007, P < 0 ·001). GGO with reticulation was less common in 9/161 (6%) and 16/322 (5%) lesions for the two pregnant groups than 24/131 (18%) for the non-pregnant adults ( P = 0 ·001, P < 0 ·001). The pulmonary involvement in children with COVID-19 was mild with a focal GGO or consolidation. Twentythree patients underwent follow-up CT, revealing progression in 9/13 (69%) at 3 days whereas improvement in 8/10 (80%) at 6-9 days after initial CT scans. Interpretation: Atypical clinical findings of pregnant women with COVID-19 could increase the difficulty in initial identification. Consolidation was more common in the pregnant groups. The clinically-diagnosed cases were vulnerable to more pulmonary involvement. CT was the modality of choice for early detection, severity assessment, and timely therapeutic effects evaluation for the cases with epidemic and clinical features of COVID-19 with or without laboratory confirmation. The exposure history and clinical symptoms were more helpful for screening in children versus chest CT.

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“…In the early stage of the disease, the lesion can manifest as round nodular-like GGO in the central area of the lung lobe, which is different from the common imaging manifestations that are patchy-like lesion in subpleural region [4][5][6]…”

mentioning

confidence: 90%

WITHDRAWN: Clinical and CT imaging features of 2019 novel coronavirus disease (COVID-19)

Zhu¹,

Liu²,

Li³

et al. 2020

Journal of Infection

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Emerging 2019 Novel Coronavirus (2019-nCoV) Pneumonia

Cited by 1,211 publications

References 12 publications

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges

Clinical and CT imaging features of the COVID-19 pneumonia: Focus on pregnant women and children

WITHDRAWN: Clinical and CT imaging features of 2019 novel coronavirus disease (COVID-19)

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