Emerging cases of pertussis among  early infants born to unvaccinated mothers, an infectious disease long absent in Northwestern Greece

Makis, Alexandros; Grammeniatis, Vasileios; Galati, Charis; Kostara, Panagiota; Petridou, Evangelia; Gartzonika, Constantina; Pappas, Athanasios; Chaliasos, Nikolaos

doi:10.4084/mjhid.2017.043

Cited by 2 publications

(2 citation statements)

References 7 publications

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“…Mean duration of hospital stay was 19 days with one child requiring intensive care unit stay due to respiratory complication. 21 In our study, pertussis was suspected based on clinical symptoms and lymphocytosis. Sixty-three percent of infants with clinically suspected pertussis were later confirmed to Survived n (%) 29 (97)…”

Section: Discussionmentioning

confidence: 91%

Lurking Infantile Pertussis: Experience from a Tertiary Care Center in Northern India

Bhattacharya

Dash

Kavitha

et al. 2020

Journal of Pediatric Infectious Diseases

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Objectives The aim is to study the clinical laboratory profile and outcome of infants with laboratory confirmed pertussis. Materials and Methods In this retrospective study, records of 30 infants with laboratory confirmed pertussis, admitted to the pediatric department of a tertiary care hospital, were reviewed. Clinical features, laboratory parameters, and outcomes were noted. Results Median (interquartile range age was 10 (7–24.5) weeks, with a male preponderance. Large majority (60%) of enrolled infants were less than 16 weeks of age and nine (30%) developed pertussis even before 8 weeks of age. Cough was universal (100%), followed by rapid breathing (73%), fever (70%), and apnea (10%). Bubble continuous positive airway pressure (CPAP), nasal prongs oxygen, and invasive ventilation were required in 15 (54%), 11 (39%), and 2 (7%) infants, respectively; 12 (40%) needed to be admitted to the pediatric intensive care unit. Anemia was observed in 28 (93%) and leukemoid reaction in 15 (50%). All except one were discharged successfully. None of the mothers had received tetanus, diphtheria, and pertussis or Tdap vaccination during pregnancy. Conclusion Our study reports the continued occurrence of infantile pertussis in the community, suggesting reconsideration of our vaccination policy, including maternal immunization.

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Section: Discussionmentioning

confidence: 91%

Lurking Infantile Pertussis: Experience from a Tertiary Care Center in Northern India

Bhattacharya

Dash

Kavitha

et al. 2020

Journal of Pediatric Infectious Diseases

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“…Nowadays, pertussis immunization in pregnancy is strongly recommended in both the USA and United Kingdom and has been recently included in the National Immunization Plan, 2017-2019 in Italy; the objective of this intervention is the prevention of pertussis infection in infants (Centers for Disease Control and Prevention, 2018;Abu Raya et al, 2015;Gabutti et al, 2015;Gabutti et al, 2017;Makis et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

Impact of Pertussis on the Italian population: Analysis of hospital discharge records in the period 2001–2014

Brosio

Kuhdari

Cocchio

et al. 2020

International Journal of Infectious Diseases

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The study aimed to analyze and update the impact of pertussis on the Italian population by evaluating pertussis-related hospital admissions in the period 2001-2014. Design or methods: Hospital Discharge Records (HDR) were provided by the National Archive of HDR data of the Ministry of Health. Only hospitalizations included in the primary diagnosis were evaluated. Significant trends over the considered years were assessed as average annual percent changes (AAPC) applying the Joinpoint model. Results: A total of 7,102 hospital admissions for pertussis (main diagnosis) were registered; the trend of hospitalizations progressively decreased from >1/100,000 inhabitants in the years 2001-2004 to 0.64/100,000 inhabitants in 2014. A great part of hospitalizations (63.6%) involved subjects <1 year of life; almost 20% of cases were registered in the age class 5-14 years. The Joinpoint analysis showed a statistically significant variation in some age classes. Conclusions: Even if this study shows a decreasing trend in the number of pertussis-related hospitalizations, the impact of the disease in Italy in terms of hospital admissions continues to be relevant, especially in the <1 year age class. Pertussis therefore continues to be, in Italy as well as in other European countries, an important public health issue.

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Emerging cases of pertussis among early infants born to unvaccinated mothers, an infectious disease long absent in Northwestern Greece

Abstract: N/A

Cited by 2 publications

References 7 publications

Lurking Infantile Pertussis: Experience from a Tertiary Care Center in Northern India

Lurking Infantile Pertussis: Experience from a Tertiary Care Center in Northern India

Impact of Pertussis on the Italian population: Analysis of hospital discharge records in the period 2001–2014

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