Emerging contaminants: A One Health perspective

Wang, Fang; Xiang, Leilei; Sze-Yin Leung, Kelvin; Elsner, Martin; Zhang, Ying; Guo, Yuming; Pan, Bo; Sun, Hongwen; An, Taicheng; Ying, Guangguo; Brooks, Bryan W.; Hou, Deyi; Helbling, Damian E.; Sun, Jianqiang; Qiu, Hao; Vogel, Timothy M.; Zhang, Wei; Gao, Yanzheng; Simpson, Myrna J.; Luo, Yi; Chang, Scott X.; Su, Guanyong; Wong, Bryan M.; Fu, Tzung-May; Zhu, Dong; Jobst, Karl J.; Ge, Chengjun; Coulon, Frederic; Harindintwali, Jean Damascene; Zeng, Xiankui; Wang, Haijun; Fu, Yuhao; Wei, Zhong; Lohmann, Rainer; Chen, Changer; Song, Yang; Sanchez-Cid, Concepcion; Wang, Yu; El-Naggar, Ali; Yao, Yiming; Huang, Yanran; Cheuk-Fung Law, Japhet; Gu, Chenggang; Shen, Huizhong; Gao, Yanpeng; Qin, Chao; Li, Hao; Zhang, Tong; Corcoll, Natàlia; Liu, Min; Alessi, Daniel S.; Li, Hui; Brandt, Kristian K.; Pico, Yolanda; Gu, Cheng; Guo, Jianhua; Su, Jianqiang; Corvini, Philippe; Ye, Mao; Rocha-Santos, Teresa; He, Huan; Yang, Yi; Tong, Meiping; Zhang, Weina; Suanon, Fidèle; Brahushi, Ferdi; Wang, Zhenyu; Hashsham, Syed A.; Virta, Marko; Yuan, Qingbin; Jiang, Gaofei; Tremblay, Louis A.; Bu, Qingwei; Wu, Jichun; Peijnenburg, Willie; Topp, Edward; Cao, Xinde; Jiang, Xin; Zheng, Minghui; Zhang, Taolin; Luo, Yongming; Zhu, Lizhong; Li, Xiangdong; Barceló, Damià; Chen, Jianmin; Xing, Baoshan; Amelung, Wulf; Cai, Zongwei; Naidu, Ravi; Shen, Qirong; Pawliszyn, Janusz; Zhu, Yong-guan; Schaeffer, Andreas; Rillig, Matthias C.; Wu, Fengchang; Yu, Gang; Tiedje, James M.

doi:10.1016/j.xinn.2024.100612

Cited by 26 publications

(2 citation statements)

References 567 publications

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“…3 Antibiotic-resistant bacteria encoding ARGs spread in various environmental ecosystems are likely to increase the resistance determinants. 4 An estimated 1.27 million deaths were directly attributable to antibiotic resistance in 2019 and may gradually evolve into the leading cause of global death. 5,6 Antibiotic resistance has been listed as one of the most emerging and pressing One Health issues.…”

Section: ■ Introductionmentioning

confidence: 99%

“…Prior to the use of antibiotics, antibiotic resistance genes (ARGs) have naturally pertained in diverse environments and shuttled among microbial populations, usually with a low abundance. , Due to the overuse/misuse of antibiotics in clinical therapy and animal husbandry, the dramatic proliferation and dissemination of ARGs, including intrinsic and acquired ones, has significantly reduced the efficacy of antibiotics for infectious diseases . Antibiotic-resistant bacteria encoding ARGs spread in various environmental ecosystems are likely to increase the resistance determinants . An estimated 1.27 million deaths were directly attributable to antibiotic resistance in 2019 and may gradually evolve into the leading cause of global death. , Antibiotic resistance has been listed as one of the most emerging and pressing One Health issues .…”

Section: Introductionmentioning

confidence: 99%

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Distinct Assembly Patterns of Soil Antibiotic Resistome Revealed by Land-Use Changes over 30 Years

Fu,

Hu,

Wang

et al. 2024

Environ. Sci. Technol.

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Compared with the ever-growing information about the anthropogenic discharge of nutrients, metals, and antibiotics on the disturbance of antibiotic resistance genes (ARGs), less is known about how the potential natural stressors drive the evolutionary processes of antibiotic resistance. This study examined how soil resistomes evolved and differentiated over 30 years in various land use settings with spatiotemporal homogeneity and minimal human impact. We found that the contents of soil organic carbon, nitrogen, soil microbial biomass, and bioavailable heavy metals, as well as related changes in the antibiotic resistome prevalence including diversity and abundance, declined in the order of grassland > cropland > bareland. Sixty-nine remaining ARGs and 14 mobile genetic elements (MGEs) were shared among three land uses. Multiple factors (i.e., soil properties, heavy metals, bacterial community, and MGEs) contributed to the evolutionary changes of the antibiotic resistome, wherein the resistome profile was dominantly driven by MGEs from both direct and indirect pathways, supported by a partial least-squares path model analysis. Our results suggest that pathways to mitigate ARGs in soils can coincide with land degradation processes, posing a challenge to the common goal of managing our environment sustainably.

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Section: ■ Introductionmentioning

confidence: 99%