Emerging native Orbitrap mass spectrometry for probing higher-order structures of proteins: Recent progress and applications

Li, Linsen; Zhang, Ying; Lv, Yueguang; Qu, Feng; Ma, Qiang

doi:10.1016/j.trac.2023.117424

TrAC Trends in Analytical Chemistry

2024

DOI: 10.1016/j.trac.2023.117424

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Emerging native Orbitrap mass spectrometry for probing higher-order structures of proteins: Recent progress and applications

Linsen Li,

Ying Zhang,

Yueguang Lv

et al.

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Cited by 3 publications

References 244 publications

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A quantitative method for aquaporin-1 protein using magnetic preconcentration and probe-based immunoassay coupling to inductively coupled plasma mass spectrometry in urine analysis

Liang,

Zhao,

Liu

et al. 2024

Analytica Chimica Acta

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A quantitative method for aquaporin-1 protein using magnetic preconcentration and probe-based immunoassay coupling to inductively coupled plasma mass spectrometry in urine analysis

Liang,

Zhao,

Liu

et al. 2024

Analytica Chimica Acta

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Advances and challenges in preparing membrane proteins for native mass spectrometry

Cheng,

Guo,

Lyu

et al. 2025

Biotechnology Advances

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Circular Economy in Manufacturing: Optimization using Lean Six Sigma

Orlov,

Hussein,

Subbarayudu

et al. 2024

E3S Web Conf.

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This research examines the amalgamation of Circular Economy concepts with Lean Six Sigma approaches to enhance manufacturing operations, emphasizing waste minimization, resource efficiency, and economic performance. The study assesses the influence of Lean Six Sigma on production efficiency and environmental sustainability via empirical analysis and process optimization methodologies. Conventional manufacturing procedures, including machining, milling, and grinding, were assessed for resource utilization and waste production, revealing that Lean Six Sigma methodologies markedly decreased material waste, especially in milling operations, where waste was curtailed by 20%. Advanced precision techniques, including CNC and laser cutting, were evaluated for their efficiency, with CNC cutting realizing a 15% decrease in energy usage and a 30% enhancement in material utilization. Laser cutting exhibited improved accuracy, resulting in a 35% decrease in rework and scrap. The economic study indicated that the application of Lean Six Sigma in CNC operations resulted in a 25% reduction in operating expenses over time, albeit greater initial expenditures. These results provide significant insights into the enhancement of industrial efficiency and the promotion of sustainable production practices via the integration of Circular Economy concepts with Lean Six Sigma methodologies. Keywords: Circular Economy, Precision Manufacturing, Comparative Analysis, Tool Life, Economic Implications.

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Emerging native Orbitrap mass spectrometry for probing higher-order structures of proteins: Recent progress and applications

Cited by 3 publications

References 244 publications

A quantitative method for aquaporin-1 protein using magnetic preconcentration and probe-based immunoassay coupling to inductively coupled plasma mass spectrometry in urine analysis

A quantitative method for aquaporin-1 protein using magnetic preconcentration and probe-based immunoassay coupling to inductively coupled plasma mass spectrometry in urine analysis

Advances and challenges in preparing membrane proteins for native mass spectrometry

Circular Economy in Manufacturing: Optimization using Lean Six Sigma

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