Emerging Organic Contaminants in Chinese Surface Water: Identification of Priority Pollutants

Zhong, Mengmeng; Wang, Tielong; Zhao, Wanying; Huang, Jun; Wang, Bin; Blaney, Lee; Bu, Qingwei; Yu, Gang

doi:10.1016/j.eng.2020.12.023

Cited by 65 publications

(15 citation statements)

References 79 publications

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“…Metformin occurs in aquatic systems with numerous other pharmaceuticals, 30,41 which are used to improve human and animal health 42,43 but, unfortunately, also induce severe endocrine disruption and antibiotic resistance among other adverse effects to aquatic biota. 44−46 Exhaustive monitoring of all pharmaceuticals is impractical because over 5000 such compounds are currently in use with new ones being continuously developed and produced.…”

Section: Introductionmentioning

confidence: 99%

“…Metformin occurs in aquatic systems with numerous other pharmaceuticals, , which are used to improve human and animal health , but, unfortunately, also induce severe endocrine disruption and antibiotic resistance among other adverse effects to aquatic biota. − Exhaustive monitoring of all pharmaceuticals is impractical because over 5000 such compounds are currently in use with new ones being continuously developed and produced . Instead, a chemical indicator can be used to track their overall contamination. , An ideal indicator should be of domestic sewage origin, omnipresent, and persistent in contaminated water but without background occurrence in clean water and have available analytical methods .…”

Section: Introductionmentioning

confidence: 99%

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Metformin Contamination in Global Waters: Biotic and Abiotic Transformation, Byproduct Generation and Toxicity, and Evaluation as a Pharmaceutical Indicator

Zhang

2022

Environ. Sci. Technol.

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Metformin is the first-line antidiabetic drug and one of the most prescribed medications worldwide. Because of its ubiquitous occurrence in global waters and demonstrated ecotoxicity, metformin, as with other pharmaceuticals, has become a concerning emerging contaminant. Metformin is subject to transformation, producing numerous problematic transformation byproducts (TPs). The occurrence, removal, and toxicity of metformin have been continually reviewed; yet, a comprehensive analysis of its transformation pathways, byproduct generation, and the associated change in adverse effects is lacking. In this review, we provide a critical overview of the transformation fate of metformin during water treatments and natural processes and compile the 32 organic TPs generated from biotic and abiotic pathways. These TPs occur in aquatic systems worldwide along with metformin. Enhanced toxicity of several TPs compared to metformin has been demonstrated through organism tests and necessitates the development of complete mineralization techniques for metformin and more attention on TP monitoring. We also assess the potential of metformin to indicate overall contamination of pharmaceuticals in aquatic environments, and compared to the previously acknowledged ones, metformin is found to be a more robust or comparable indicator of such overall pharmaceutical contamination. In addition, we provide insightful avenues for future research on metformin.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Metformin Contamination in Global Waters: Biotic and Abiotic Transformation, Byproduct Generation and Toxicity, and Evaluation as a Pharmaceutical Indicator

Zhang

2022

Environ. Sci. Technol.

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“…This application can assist the personnel team and company management in monitoring employee's absence and as a performance measurement material to assess Key Performance Indicators (KPI). Value engineering is a method of evaluating, analysing the advantages, dangers, and limitations of each alternative to complete the decision-making process [22], one of which is Determination of Application Feature Innovation Priority Alternatives. For this reason, it is necessary to apply value engineering methods in the development of application features.…”

Section: Introductionmentioning

confidence: 99%

Optimization of Innovation Features in Mobile-Based Attendance Application

Katrilia

Anggoro

Sp.

2022

Management Systems in Production Engineering

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Improved Human Resources Performance can be realized in the employee’s absence. The sophistication of technology to accommodate the absence is the use of a Mobile-Based Attendance Application. Attendance can be used to measure employee performance. One of the measuring tools in measuring performance is the Key Performance Indicator (KPI). KPI values can be obtained from the Mobile-based Attendance Application, as currently implemented by an IT Company. But in its development, there is a shortage on the application features of Daily Attendance, Leave, Report Recaps Attendance and Report Recaps Leave. The value engineering method with the Analytical Hierarchy Process is used in this paper to obtain prioritized alternatives in the development of application feature updates. The results of the research show that the alternative with the largest percentage is owned by Alternative IV (45.6%). These results indicate that this alternative can be used as a recommendation for renewal of attendance application features on IT Company. Alternative IV shows optimal results such as the realization of application feature requirements for users, consumption of fewer workdays for 1-2 days, low costs, easy-to-understand feature design, and uncomplicated programming techniques.

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“…These micropollutants are detected in various aquatic environments and are currently listed among the top priority emerging organic contaminants based on five different prioritization schemes. 33 On the other hand, 4-propylphenol (4-PP) represents one of many alkylphenols used in personal care products. Similar to -ED, 4-PP 𝜷 also has endocrine disrupting capability.…”

Section: Introductionmentioning

confidence: 99%

Emerging environmental contaminants at the air/aqueous and biological soft interfaces

Pozza

Deardorff

Subir

2022

Environ. Sci.: Adv.

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Emerging Organic Contaminants in Chinese Surface Water: Identification of Priority Pollutants

Cited by 65 publications

References 79 publications

Metformin Contamination in Global Waters: Biotic and Abiotic Transformation, Byproduct Generation and Toxicity, and Evaluation as a Pharmaceutical Indicator

Metformin Contamination in Global Waters: Biotic and Abiotic Transformation, Byproduct Generation and Toxicity, and Evaluation as a Pharmaceutical Indicator

Optimization of Innovation Features in Mobile-Based Attendance Application

Emerging environmental contaminants at the air/aqueous and biological soft interfaces

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