2023
DOI: 10.3748/wjg.v29.i15.2241
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Emerging role of non-invasive and liquid biopsy biomarkers in pancreatic cancer

Abstract: A global increase in the incidence of pancreatic cancer (PanCa) presents a major concern and health burden. The traditional tissue-based diagnostic techniques provided a major way forward for molecular diagnostics; however, they face limitations based on diagnosis-associated difficulties and concerns surrounding tissue availability in the clinical setting. Late disease development with asymptomatic behavior is a drawback in the case of existing diagnostic procedures. The capability of cell free markers in disc… Show more

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Cited by 7 publications
(2 citation statements)
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“…WJG v29i15: The articles are interesting overall. For “Editor’s choice” papers, I especially like two: (1) Pancreatic cancer topic: “Emerging role of non-invasive and liquid biopsy biomarkers in pancreatic cancer”[ 37 ], because of the importance of the topic; and (2) Gastrointestinal barrier dysfunction topic: “Mechanisms of gastrointestinal barrier dysfunction in COVID-19 patients”[ 38 ].…”
Section: Hot Articles and Insufficient Articlesmentioning
confidence: 99%
“…WJG v29i15: The articles are interesting overall. For “Editor’s choice” papers, I especially like two: (1) Pancreatic cancer topic: “Emerging role of non-invasive and liquid biopsy biomarkers in pancreatic cancer”[ 37 ], because of the importance of the topic; and (2) Gastrointestinal barrier dysfunction topic: “Mechanisms of gastrointestinal barrier dysfunction in COVID-19 patients”[ 38 ].…”
Section: Hot Articles and Insufficient Articlesmentioning
confidence: 99%
“…Thus, there are high expectations for using microvesicles isolated from serum or FNA to diagnose pancreatic cancer. A recently published review by Bararia et al provides a comprehensive description of the novel biomarkers that have the potential to be used as noninvasive means of discriminating pancreatic cancer from precancerous lesions, thereby improving the diagnosis of early stage PDAC [ 51 ].…”
Section: Improvements To Current Diagnostic Approachesmentioning
confidence: 99%