“…In recent years, the involvement and role of adipokines are emerging to the forefront in the field of fertility and reproduction. Many studies suggested that adipokines such as leptin (Spicer, 2001; Tersigni et al, 2011), visfatin (Annie et al, 2020; Reverchon et al, 2013), resistin (Maillard et al, 2011; Niles et al, 2012; Reverchon et al, 2013), adiponectin (Chabrolle et al, 2007; Ledoux et al, 2006; Lord et al, 2005; Schmidt et al, 2008; Takemura et al, 2006), chemerin (Carlino et al, 2012; Goralski et al, 2007; Reverchon et al, 2012) and apelin (Kurowska et al, 2018; Roche et al, 2016; Shokrollahi et al, 2022; Wang et al, 2020) are expressed and play important role in ovary, uterus, placenta. Apelin is expressed in various types of tissues and organs such as the central nervous system and peripheral tissues, including the hypothalamus, adipose tissue, skeletal muscle, digestive system, ovary, uterus, placenta and mammary gland (Cobellis et al, 2007; Mercati et al, 2018).…”