Emerging Roles of Coronavirus in Autoimmune Diseases

Zhou, Si Yu; Zhang, Chi; Shu, Wen; Chong, Li Ye; He, Jun; Xu, Zhiwei; Pan, Hai

doi:10.1016/j.arcmed.2021.03.012

Cited by 19 publications

(27 citation statements)

References 54 publications

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“…61 Coronavirus may induce autoimmune diseases caused by a considerable increase in proinflammatory cytokines and chemokines in the infected person's serum. 62 Accordingly, a virus-triggered immunopathology may advance demyelinating disorders, such as multiple sclerosis (MS). 63 Similar results were obtained in animal models confirming the role of coronaviruses in demyelination and intracranial axonal degeneration.…”

Section: Covid-19 and Rheumatology/immunologymentioning

confidence: 99%

The overall impact of COVID‐19 on healthcare during the pandemic: A multidisciplinary point of view

Sabetkish

Rahmani

2021

Health Science Reports

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Background and Aims The Coronavirus disease 2019 (COVID‐19) pandemic globally changed the priorities of medical and surgical procedures. It has caused many healthcare systems to stop performing their routine screenings. Altering medical clinics to COVID‐19 referral centers, lockdowns, and the public fear to refer to medical centers caused a significant reduction in the referral rate; especially in the elderly. This short review article highlights the transform in clinical practice during the post‐COVID era and the need for future medical revolutions. Methods A comprehensive literature search was separately performed by both authors. The articles published between 2019 and August 2021 were included in this study and selected according to a quality appraisal method. Results We have summarized the possible corresponding changes in the diagnosis and treatment of all fields of medical care including internal medicine, surgical, and minor subcategories after the COVID‐19 pandemic. We have also discussed the potential impacts of the pandemic on all these different categories and subcategories of medicine, including the outpatient setting and clinical work. We do believe that the lack of routine check‐ups has led to an increase in the stage of disease in patients with a previously diagnosed problem. On the other hand, the dramatic change in the lifestyle of the population including restricted mobility and increased consumption of unhealthy food has caused metabolic syndrome and other new diseases that have not been diagnosed and properly managed. Conclusion Our findings revealed the urgent need for public health awareness. It indicated the need to carry out both psychological and screening approaches in the post‐COVID era to not miss patients with a chronic disease and new cases who were undiagnosed during the COVID pandemic.

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Section: Covid-19 and Rheumatology/immunologymentioning

confidence: 99%

The overall impact of COVID‐19 on healthcare during the pandemic: A multidisciplinary point of view

Sabetkish

Rahmani

2021

Health Science Reports

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“…There are seven coronaviruses of varying pathogenicity that can infect humans ( 15 ). Autoimmune diseases concomitant with coronaviruses have been suggested to be associated with cross-reactivity of antibodies or activated lymphocytes with different antigens which own the same or similar epitopes ( 16 ). Two cases of pemphigus vulgaris following SARS-CoV-2 infection, as well as BP in an elderly female and a middle-aged female with COVID-19 were reported ( 17 – 20 ).…”

Section: Discussionmentioning

confidence: 99%

Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative

et al. 2021

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Bullous pemphigoid (BP) is a cutaneous disease triggered by numerous stimuli, where genetic milieu-influenced autoimmunity to hemidesmosomal proteins, namely, BP180 and/or BP230 initiate an inflammation leading to dermal-epidermal junction (DEJ) enzymatic pathological remodelling. Here, to the best of our knowledge, we present the first case of an infantile BP apparently triggered by COVID-19. BP should be included in differential diagnosis of infantile rashes showing blisters or vesicles or both as well as their prodromal and evolutionary lesions. Possible triggers, such as coronavirus disease 2019 (COVID-19), of BP in infancy should be identified and properly dealt with.

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“…Das ausgeprägte immunogene Potenzial des Virus deutet eine potenzielle Beteiligung an multiplen autoimmunen Erkrankungen und Exazerbationen derselben an [14].…”

Section: Pathophysiologische Mechanismenunclassified

Update 2021: COVID-19 aus Sicht der Neurologie

Simon¹,

Menzler²,

Timmermann³

2021

Dtsch Med Wochenschr

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Der überwiegende Teil der Patienten mit einer COVID-19-Erkrankung zeigt im Verlauf neurologische Symptome. Des Weiteren entwickelt sich, teils auch nach unkomplizierten Verläufen, das sogenannte Post-COVID-Syndrom mit langanhaltenden Symptomen. In diesem Artikel möchten wir einen Überblick über den aktuellen Stand der neurologischen Beteiligung im Rahmen der SARS-CoV-2-Infektion geben. Patientenversorgung und spezielle Patientengruppen Im Rahmen der ersten Welle kam es zu Einschränkungen der ambulanten und stationären Patientenversorgung. Die Rate an Krankenhauseinweisungen, z. B. für zerebrovaskuläre Ereignisse, nahm ab und die Mortalität stieg. Weiterhin sind besonders im ambulanten Bereich Konzepte wie z. B. telemedizinische Konsultationen zur Abwendung einer Unterversorgung unumgänglich.

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Emerging Roles of Coronavirus in Autoimmune Diseases

Cited by 19 publications

References 54 publications

The overall impact of COVID‐19 on healthcare during the pandemic: A multidisciplinary point of view

The overall impact of COVID‐19 on healthcare during the pandemic: A multidisciplinary point of view

Case Report: Infantile Bullous Pemphigoid: Triggering by COVID-19 Is Speculative

Update 2021: COVID-19 aus Sicht der Neurologie

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