Emerging strategies for synthesis of heterocyclic compounds enabled by titanium oxide nanoparticles as heterogeneous catalyst

Dixit, Vaishali; Kumar, Gourav; Kumar, Parveen; Soni, Akta; Nemiwal, Meena

doi:10.1016/j.tet.2024.134039

Tetrahedron

2024

DOI: 10.1016/j.tet.2024.134039

|View full text |Cite

Emerging strategies for synthesis of heterocyclic compounds enabled by titanium oxide nanoparticles as heterogeneous catalyst

Vaishali Dixit,

Gourav Kumar,

Parveen Kumar

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

2025

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 155 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Biomass-derived zirconium composite: An adsorbent for preferential removal of heavy metals and contaminants in wastewater

Baldev,

Kumar,

Sharma

et al. 2025

Journal of Water Process Engineering

View full text Add to dashboard Cite

Biomass-derived zirconium composite: An adsorbent for preferential removal of heavy metals and contaminants in wastewater

Baldev,

Kumar,

Sharma

et al. 2025

Journal of Water Process Engineering

View full text Add to dashboard Cite

Catalyzed syntheses of novel series of spiro thiazolidinone derivatives with nano Fe2O3: spectroscopic, X-ray, Hirshfeld surface, DFT, biological and docking evaluations

Abbass,

El-Rayyes,

Khalil Ali

et al. 2024

Sci Rep

View full text Add to dashboard Cite

Twelve spiro thiazolidinone compounds ( A–L ) were synthesized via either conventional thermal or ultrasonication techniques using Fe 2 O 3 nanoparticles. The modification of the traditional procedure by using Fe 2 O 3 nanoparticles led to enhancement of the yield of the desired candidates to 78–93% in approximately half reaction time compared with 58–79% without catalyst. The products were fully characterized using different analytical and spectroscopic techniques. The structure of the two derivatives 4-phenyl-1-thia-4-azaspirodecan-3-one ( A ) and 4-(p-tolyl)-1-thia-4-azaspirodecan-3-one ( B ) were also determined using single crystal X-ray diffraction and Hirshfeld surface analysis. The two compounds ( A and B ) were crystallized in the orthorhombic system with Pbca and P2 1 2 1 2 1 space groups, respectively. In addition, the crystal packing of compounds revealed the formation of supramolecular array with a net of intermolecular hydrogen bonding interactions. The energy optimized geometries of some selected derivatives were performed by density functional theory (DFT/B3LYP). The reactivity descriptors were also calculated and correlated with their biological properties. All the reported compounds were screened for antimicrobial inhibitions. The two derivatives, F and J , exhibited the highest levels of bacterial inhibition with an inhibition zone of 10–17 mm. Also, the two derivatives, F and J , displayed the most potent fungal inhibition with an inhibition zone of 15–23 mm. Molecular docking investigations of some selected derivatives were performed using a B-DNA (PDB: 1BNA) as a macromolecular target. Structure and activity relationship of the reported compounds were correlated with the data of antimicrobial activities and the computed reactivity parameters.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Emerging strategies for synthesis of heterocyclic compounds enabled by titanium oxide nanoparticles as heterogeneous catalyst

Cited by 2 publications

References 155 publications

Biomass-derived zirconium composite: An adsorbent for preferential removal of heavy metals and contaminants in wastewater

Biomass-derived zirconium composite: An adsorbent for preferential removal of heavy metals and contaminants in wastewater

Catalyzed syntheses of novel series of spiro thiazolidinone derivatives with nano Fe2O3: spectroscopic, X-ray, Hirshfeld surface, DFT, biological and docking evaluations

Contact Info

Product

Resources

About