2024
DOI: 10.3389/fimmu.2024.1438984
|View full text |Cite
|
Sign up to set email alerts
|

Emerging therapeutic strategies targeting extracellular histones for critical and inflammatory diseases: an updated narrative review

Tinghang Yang,
Jing Peng,
Zhuyun Zhang
et al.

Abstract: Extracellular histones are crucial damage-associated molecular patterns involved in the development and progression of multiple critical and inflammatory diseases, such as sepsis, pancreatitis, trauma, acute liver failure, acute respiratory distress syndrome, vasculitis and arthritis. During the past decade, the physiopathologic mechanisms of histone-mediated hyperinflammation, endothelial dysfunction, coagulation activation, neuroimmune injury and organ dysfunction in diseases have been systematically elucida… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 215 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?