Emissions from heated indoor dust: an approach for sample preparation and in vitro toxicity testing

Mathiesen, Mette; Pedersen, Ellen K.; Urfjell, Bente; Bjørseth, Olav; Syversen, Tore

doi:10.1016/s1352-2310(03)00575-2

Cited by 2 publications

(1 citation statement)

References 30 publications

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“…During heating of dust samples in our laboratory hot‐surface model, three fractions are generated: (i) the remains of the heated dust sample, denoted residuals, (ii) the emissions volatile at room temperature, and (iii) the condensate, condensed vapors of emissions. We developed in vitro methods for testing the biologic effect of emissions from heated dust at temperatures realistic for indoor equipment (Mathiesen et al., 2003a,b). These emissions proved to have a toxic effect in the cell cultures applied.…”

Section: Introductionmentioning

confidence: 99%

Heating of indoor dust causes reduction in its ability to stimulate release of IL-8 and TNFalpha in vitro compared to non-heated dust

Mathiesen

Pedersen

Bjørseth³

et al. 2004

Indoor Air

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Accumulation of indoor dust on electric heaters and light fixtures may produce a bad odor when switched on in the cold season and some people claim respiratory distress during such events. To investigate to what extent the residuals of heated indoor dust represent a health hazard, we measured the effect in cell cultures before and after heat treatment of the dust. The in vitro results imply that the residual dust will cause a lower proinflammatory response in the airways if suspended and inhaled compared with non-heated dust. This is partly explained by heat destruction of inflammatory components in the dust.

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Section: Introductionmentioning

confidence: 99%