Emotion affects action: Midcingulate cortex as a pivotal node of interaction between negative emotion and motor signals

Pereira, Mirtes Garcia; Oliveira, Letícia; Erthal, Fátima Smith; Joffily, Mateus; Mocaiber, Izabela; Volchan, Eliane; Pessoa, Luiz

doi:10.3758/cabn.10.1.94

Cited by 126 publications

(121 citation statements)

References 71 publications

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“…MCC is an important site for the integration of negative emotions and motor signals in the brain as it receives widespread inputs from emotion related brain regions, and is known to have projections towards motor centres such as primary motor cortex, and supplementary motor areas. 51 The MCC has been reported to be activated during rectal distension among patients with IBS in a meta-analysis. 39 It has been implicated in the regulation of autonomic activity and emotional perception.…”

Section: Discussionmentioning

confidence: 99%

Mapping of Brain Activations to Rectal Balloon Distension Stimuli in Male Patients with Irritable Bowel Syndrome Using Functional Magnetic Resonance Imaging

Guleria

Karyampudi

Singh

et al. 2017

J Neurogastroenterol Motil

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Background/AimsIrritable bowel syndrome (IBS) is associated with exaggerated cerebral response including emotional processing following visceral stimulation; though data on this issue is available in female IBS patients, it is scanty among males. Hence, we aimed to study brain response of male IBS patients following rectal balloon distension as compared to healthy controls using functional magnetic resonance imaging (fMRI). Data between diarrhea and constipation predominant IBS (IBS-D and IBS-C) were also compared. MethodsRectal balloon distension threshold was assessed in 20 male IBS patients (10 IBS-C and 10 IBS-D) and 10 age-matched male healthy controls. Subsequently, fMRI on all the participants was performed at their respective rectal pain threshold. The fMRI data were analysed using the Statistical Parametric Mapping software. ResultsIBS patients showed greater cerebral activations in insula, middle temporal gyrus, and cerebellum in the left hemisphere compared to healthy controls. Neural activation was found in bilateral precuneus/superior parietal lobules in controls but not in patients with IBS. The brain activation differed among IBS-C and IBS-D patients; while the right mid-cingulate cortex was activated in IBS-C, the left inferior orbito-frontal cortex, left calcarine, and bilateral fusiform gyri were activated among patients with IBS-D following rectal balloon distension. Conclusions

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Section: Discussionmentioning

confidence: 99%

Mapping of Brain Activations to Rectal Balloon Distension Stimuli in Male Patients with Irritable Bowel Syndrome Using Functional Magnetic Resonance Imaging

Guleria

Karyampudi

Singh

et al. 2017

J Neurogastroenterol Motil

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“…For example, whilst most studies seem to report an increase in the BOLD response during the critical interaction condition (Blair, Smith et al 2007, Pereira, de Oliveira et al 2010, other studies have reported a paradoxical signal decrease McCarthy 2006, Fruhholz, Fehr et al 2009). Discrepancy also extends to the behavioral outcome of dealing with emotion during a standard cognitive control task.…”

Section: Introductionmentioning

confidence: 99%

Probing emotional influences on cognitive control: an ALE meta-analysis of cognition emotion interactions

2013

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Increasing research documents an integration of cognitive control and affective processes. Despite a surge of interest in investigating the exact nature of this integration, no consensus has been reached on the precise neuroanatomical network involved. Using the Activation Likelihood Estimation meta-analysis method, we examined 43 functional Magnetic Resonance Imaging (fMRI) studies (total number of foci = 332; total number of participants, N =820) from the literature that have reported significant interactions between emotion and cognitive control. Metaanalytic results revealed that concurrent emotion (relative to emotionally neutral trials) consistently increased neural activation during high relative to low cognitive control conditions across studies and paradigms. Specifically, these activations emerged in regions commonly implicated in cognitive control such as the lateral prefrontal cortex (inferior frontal junction, inferior frontal gyrus), the medial prefrontal cortex, and the basal ganglia. In addition, some areas emerged during the interaction contrast that were not present during one of the main effects and included the subgenual anterior cingulate cortex and the precuneus. These data provide new evidence for a network of cognition emotion interaction within a cognitive control setting. The findings are discussed within current theories of cognitive and attentional control.

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“…For example, when a person is frightened, this fear is often accompanied by a protective movement such as raising one's hands in front of one's face when threatened or jumping away when startled. Given the instinctive nature and clear survival value of such actions, it is reasonable to assume that movements linked to emotional responses would receive preferential processing in brain areas related to motoric activity much in the same way that emotional stimuli receive prioritized attentional processing (Pereira et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

Emotion-dependent responses in spinal cord neurons: A spinal fMRI study

Smith

Kornelsen

2011

NeuroImage

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Previous research has demonstrated that emotional stimuli receive preferential processing in the brain. In the current study, functional magnetic resonance imaging was utilized to determine if emotion-specific responses are detectable in the cervical spinal cord. During the passive (i.e., non-motoric) perception of images, activity was detected in the left dorsal and right ventral spinal cord in response to negative emotional stimuli; however, this pattern was reversed in response to neutral and positive stimuli. Critically, during active motoric responses to images, there was greater activity in the ventral cervical spinal cord in response to negative emotional stimuli than to neutral stimuli. These results demonstrate preferential motor responses to negative emotional images by the spinal cord, likely indicating an enhancement of activity in response to threat. Research highlights Activity in the cervical spinal cord is influenced by emotional images.  Positive and negative images elicit opposite patterns of activity during perception.  Threatening images increase activity in the cervical spinal cord during movements.  Activity occurs in the ventral aspect of the cord during the negative condition.  Activity is lateralized to the side producing movement in the negative condition.

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Emotion affects action: Midcingulate cortex as a pivotal node of interaction between negative emotion and motor signals

Cited by 126 publications

References 71 publications

Mapping of Brain Activations to Rectal Balloon Distension Stimuli in Male Patients with Irritable Bowel Syndrome Using Functional Magnetic Resonance Imaging

Mapping of Brain Activations to Rectal Balloon Distension Stimuli in Male Patients with Irritable Bowel Syndrome Using Functional Magnetic Resonance Imaging

Probing emotional influences on cognitive control: an ALE meta-analysis of cognition emotion interactions

Emotion-dependent responses in spinal cord neurons: A spinal fMRI study

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