Emotional modulation of pain: A clinical perspective

Klossika, Iris; Flor, Herta; Kamping, Sandra; Bleichhardt, Gaby; Trautmann, N.; Treede, Rolf‐Detlef; Bohus, Martin; Schmahl, Christian

doi:10.1016/j.pain.2006.08.007

Cited by 76 publications

(38 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Section: Cortico-limbic Pathwaymentioning

confidence: 99%

“…This pathway integrates sensory pain characteristics with information from other sensory systems as well as learning and memory, thus adding a cognitive aspect regarding long-term consequences to affective pain processing [66,67] . According to this corticolimbic pathway, an indirect route for pain signals into the HF is naturally expected: the interaction or crosstalk between the lateral and medial system [66] . To note, the insula is one critical region in this cortico-limbic pathway and the efferents from the insula supply the HF via its projection to the parahippocampal region, among which is the EC [64,65] .…”

Section: Cortico-limbic Pathwaymentioning

confidence: 99%

See 1 more Smart Citation

Roles of the hippocampal formation in pain information processing

2009

View full text Add to dashboard Cite

Abstract:Pain is a complex experience consisting of sensory-discriminative, affective-motivational, and cognitive-evaluative dimensions. Now it has been gradually known that noxious information is processed by a widely-distributed, hierarchicallyinterconnected neural network, referred to as neuromatrix, in the brain. Thus, identifying the multiple neural networks subserving these functional aspects and harnessing this knowledge to manipulate the pain response in new and beneficial ways are challenging tasks. Albeit with elaborate research efforts on the cortical responses to painful stimuli or clinical pain, involvement of the hippocampal formation (HF) in pain is still a matter of controversy. Here, we integrate previous animal and human studies from the viewpoint of HF and pain, sequentially representing anatomical, behavioral, electrophysiological, molecular/ biochemical and functional imaging evidence supporting the role of HF in pain processing. At last, we further expound on the relationship between pain and memory and present some unresolved issues.

show abstract

Section: Cortico-limbic Pathwaymentioning

confidence: 99%

Section: Cortico-limbic Pathwaymentioning

confidence: 99%

Roles of the hippocampal formation in pain information processing

2009

View full text Add to dashboard Cite

show abstract

“…These pathways, which activate in parallel as well as serially, include the spinohypothalamic, spinoamygdaloid, and spinothalamic pathways. These and other pathways have projections to specific thalamic nuclei that connect to the anterior cingulate cortex (ACC) and the insular cortex (IC) of the limbic system and also through corticolimbic pathways from the sensory cortex to brain structures involved in other sensory modalities (hearing, smell, and vision) and memory (Price 2000;Klossika et al 2006). Spinoamygdaloid projections seem to influence fear and avoidance; spinothalamic projections to the parietal lobe identify the location of a pain stimulus while projections to the insular cortex provide information about pain intensity.…”

Section: Biological Mechanisms Of Physical Pain Processingmentioning

confidence: 99%

Invited Commentary: Understanding Brain Mechanisms of Pain Processing in Adolescents’ Non-Suicidal Self-Injury

Ballard

Bosk

Pao

2009

J Youth Adolescence

View full text Add to dashboard Cite

Whereas non-suicidal self injury (NSSI) is reported in 13-23% of adolescents and is an increasingly studied topic, there has been little investigation into the pathophysiology behind self-injury. This commentary examines recent research into pain and emotional distress to discuss implications for the manner we should understand, research, and treat NSSI in the future. Research indicates that adolescents may be particularly vulnerable to NSSI behaviors due to neurodevelopmental changes in the processing of distress and pain. Additionally, emotional distress and physical pain neural pathways may have been altered in these individuals, leading to the development of NSSI behaviors during adolescence when changes in ongoing brain development may lead to further emotional dysregulation and poor impulse control. Further studies that directly characterize the relationship between emotional distress and physical pain in adolescence, as well as the neural differences between self-injurers and non-selfinjurers, are needed.

show abstract

“…Several authors (de Wied and Verbaten, 2001;Meagher et al, 2001;Rainville et al, 2005) agree that pleasant affective states reduce pain perception, whereas unpleasant affective states exacerbate it. Consistently, dysfunctional emotional and cognitive processing has an important influence on pain perception (Klossika et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Changes in self-perceived role identity modulate pain perception

Kut

Schaffner

Wittwer

et al. 2007

Pain

View full text Add to dashboard Cite

Pain is an experience including physiological and psychological factors. We assume that emotions may be elicited and increased through self-perceived role identity and that change of role identity alters quality and intensity of pain perception. We used role-play strategies to assess whether pain can be better tolerated whenever, in an unavoidable and unpleasant context, role identity confers pain a meaningful and thus suitable character. We induced antithetic roles in 21 actors who received heat stimuli on their arms before and after role-play conditions. Pain tolerance, skin conductance and voice signals were measured. Pain tolerance increased for heroes/heroines and decreased for faint-hearts. Men showed higher pain tolerance. Heroes/heroines evaluated heat stimuli as more intense. Faint-hearts found pain stimuli more affectively loaded at lower temperatures. Women showed higher pain ratings. Hence, self-perception influences pain perception. Role-play strategies may be of value for new pain management strategies. AbstractPain is an experience including physiological and psychological factors. We assume that emotions may be elicited and increased through self-perceived role identity and that change of role identity alters quality and intensity of pain perception. We used role-play strategies to assess whether pain can be better tolerated whenever, in an unavoidable and unpleasant context, role identity confers pain a meaningful and thus suitable character. We induced antithetic roles in 21 actors who received heat stimuli on their arms before and after role-play conditions. Pain tolerance, skin conductance and voice signals were measured. Pain tolerance increased for heroes/heroines and decreased for faint-hearts. Men showed higher pain tolerance. Heroes/heroines evaluated heat stimuli as more intense. Faint-hearts found pain stimuli more affectively loaded at lower temperatures. Women showed higher pain ratings. Hence, self-perception influences pain perception. Role-play strategies may be of value for new pain management strategies. Ó

show abstract

Emotional modulation of pain: A clinical perspective

Cited by 76 publications

References 35 publications

Roles of the hippocampal formation in pain information processing

Roles of the hippocampal formation in pain information processing

Invited Commentary: Understanding Brain Mechanisms of Pain Processing in Adolescents’ Non-Suicidal Self-Injury

Changes in self-perceived role identity modulate pain perception

Contact Info

Product

Resources

About