Cognitive models of psychopathology posit that the content or focus of information-processing biases (e.g., attentional biases) is disorder-specific: Depression is hypothesized to be characterized by attentional biases specifically for depression-relevant stimuli (e.g. sad facial expressions), whereas anxiety should relate particularly to attentional biases to threat-relevant stimuli (e.g., angry faces). However, little research has investigated this specificity hypothesis, and none with a sample of youth. The present study examined attentional biases to emotional faces (sad, angry, and happy compared with neutral) in groups of pure depressed, pure anxious, comorbid depressed and anxious, and control youth (ages 9-17; N = 161). Consistent with cognitive models, pure depressed and pure anxious youth exhibited attentional biases specifically to sad and angry faces, respectively, while comorbid youth exhibited attentional biases to both facial expressions. In addition, control youth exhibited attentional avoidance of sad faces, and comorbid boys avoided happy faces. Overall, findings suggest that cognitive biases and processing of particular emotional information are specific to pure clinical depression and anxiety, and results inform etiological models of potentially specific processes that are associated with internalizing disorders among youth.Major depressive disorder (MDD) is a common disorder with increasingly higher prevalence rates starting in adolescence (Avenevoli et al., 2008;Costello et al., 2003;Hankin et al., 1998). Depression frequently co-occurs with other psychiatric disorders, especially anxiety disorders (median odds-ratio of 8.2; Angold, Costello, & Erkanli, 1999). Comorbid depression is associated with more severe symptoms, consequences, and worse clinical course and potential treatment outcomes (Birmaher et al. 1996;Lewinsohn et al. 1995). However, the specificity of etiological processes that are associated with pure clinical depression compared with depression comorbid with anxiety disorders is not well understood, and enhanced Correspondence concerning this article should be addressed to Benjamin L. Hankin, Department of Psychology, University of Denver, 2155 South Race Street, Denver CO 80208. Internet correspondence can be addressed to ben.hankin@psy.du.edu. Publisher's Disclaimer: The following manuscript is the final accepted manuscript. It has not been subjected to the final copyediting, fact-checking, and proofreading required for formal publication. It is not the definitive, publisher-authenticated version. The American Psychological Association and its Council of Editors disclaim any responsibility or liabilities for errors or omissions of this manuscript version, any version derived from this manuscript by NIH, or other third parties. The published version is available at www.apa.org/pubs/journals/ABN.
NIH Public AccessAuthor Manuscript J Abnorm Psychol. Author manuscript; available in PMC 2011 August 1.
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