Empirical assessment of the self-medication hypothesis among dually diagnosed inpatients

Castañeda, Ricardo

doi:10.1016/0010-440x(94)90189-9

Cited by 45 publications

(31 citation statements)

References 14 publications

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“…24 In general, substance abusers frequently characterize their use as a means for coping with psychiatric symptoms. [25][26][27] Among marijuana users, coping motives have been found to be associated with a variety of anxiety-related constructs: agoraphobic cognitions, anxiety arousal, 27 affective liability, 28 negative affect, 29 and worry. 24 Little is known however, about the relationship between coping motives and GAD, the most common anxiety disorder among women.…”

Section: Marijuana Use Anxiety and Coping Expectanciesmentioning

confidence: 99%

General Anxiety Disorder Symptoms, Tension Reduction, and Marijuana Use Among Young Adult Females

Dios¹,

Hagerty

Herman

et al. 2010

Journal of Women's Health

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Section: Marijuana Use Anxiety and Coping Expectanciesmentioning

confidence: 99%

General Anxiety Disorder Symptoms, Tension Reduction, and Marijuana Use Among Young Adult Females

Dios¹,

Hagerty

Herman

et al. 2010

Journal of Women's Health

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“…For instance, some drugdependent people seek out opioids to calm underlying feelings of anger, rage or aggression -utilizing the 'analgesic properties' of the substance in a broad sense. Cocaine is sought out primarily by some people for the drug's ability to alleviate psychological distress associated with depression and attention defi cit disorder [79,83,86] .…”

Section: The Eye That Might See: Comorbidity and Self-medicationmentioning

confidence: 99%

Eyes Wide Shut? – A Conceptual and Empirical Critique of Methadone Maintenance Treatment

et al. 2004

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Background: Methadone maintenance treatment (MMT) has been the ‘gold standard’ pharmacotherapy treatment for illicit opioid dependence for over 30 years. It has been widely evaluated, and is generally claimed to be ‘effective’. Methods: The objective of this paper is to review the rationale of MMT as an intervention for a biomedical disorder with primary social objectives as well as the methodological quality and evidence of MMT outcome research. Data sources included opioid dependence treatment practice, review and outcome research literature (1965–2001) in the form of peer-reviewed articles, books, monographs and reports that are preeminently cited and reviewed international studies on MMT. Results/Data Synthesis: Rigorous and appropriate evaluation (i.e., RCTs, intent-to-treat, patient-centered) methods in MMT evaluations are rare. Evidence of MMT’s effectiveness on primary treatment objectives is mixed and appears to be largely partial and short-term. Positive outcomes may be the result of selection effects of compliant patients and loss in proportion when more rigorous standards of analysis are applied. Conclusions: The quality of existing MMT research, and evidence for its general effectiveness are limited. Key concepts of self-medication and psychiatric comorbidity are largely ignored in MMT treatment and research frameworks, although they may serve to explain MMT’s limited treatment success. Emerging new opioid pharmacotherapies require the fundamental review of the existing MMT paradigm as well as the application of rigorous and appropriate evaluation methods for future treatment.

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“…Hence for opiates, there is support for self-medication. 33 Another study in schizophrenics did not find any link between specific substance use and specific symptoms. 15 Also, the reasons for drug use reported by the schizophrenic and non-schizophrenic subjects are similar.…”

Section: The Vulnerability Model Hypothesizes That Drug Abusementioning

confidence: 94%

Comparison of Sociodemographic and Clinical Variables in Schizophrenics With and Without Substance Abuse

Rajashekharaiah¹,

Verma²

2016

jemds

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Empirical assessment of the self-medication hypothesis among dually diagnosed inpatients

Cited by 45 publications

References 14 publications

General Anxiety Disorder Symptoms, Tension Reduction, and Marijuana Use Among Young Adult Females

General Anxiety Disorder Symptoms, Tension Reduction, and Marijuana Use Among Young Adult Females

Eyes Wide Shut? – A Conceptual and Empirical Critique of Methadone Maintenance Treatment

Comparison of Sociodemographic and Clinical Variables in Schizophrenics With and Without Substance Abuse

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