Employing Active Learning in Medium Optimization for Selective Bacterial Growth
Shuyang Zhang,
Honoka Aida,
Bei-Wen Ying
Abstract:Medium optimization and development for selective bacterial cultures are essential for isolating and functionalizing individual bacteria in microbial communities; nevertheless, it remains challenging due to the unknown mechanisms between bacterial growth and medium components. The present study first tried combining machine learning (ML) with active learning to fine-tune the medium components for the selective culture of two divergent bacteria, i.e., Lactobacillus plantarum and Escherichia coli. ML models cons… Show more
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