Empty nose syndrome: A literature review

Косяков, С. Я.; Kirdeeva, A. I.

doi:10.17116/rosrino201523262-67

Cited by 2 publications

(1 citation statement)

References 30 publications

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“…Местно применяют различные ирригационные процедуры, чаще всего изотоническим раствором, местные аппликации масляными и мазевы-ми препаратами. Были попытки имплантации под мукопериост различных ауто-, гомо-, гетерои аллопластических материалов, которые в подавляющем большинстве случаев рассасывались, нагнаивались, секвестрировались и отторгались, что еще больше усугубляло течение заболевания [2,[9][10][11][12]. Таким образом, при видимой простоте, проблема помощи этим пациентам остается открытой.…”

Section: ;19;4(107)unclassified

Evaluation of efficacy of the Olyfrin spray in treatment of patients with atrophic rhinitis using the Russian-language version of SNOT-25 questionnaire with Houser's modifications

Chuchueva¹,

Савлевич²,

Козлов³

et al. 2020

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Atrophic rhinitis at the same time significantly reduces the quality of life of patients suffering from it and is a refractory pathology. The current therapy for the disease includes conservative and sometimes surgical treatment. Nevertheless, the problem of effective therapeutic method remains to be relevant and requires the search for new medicines. Also, there is no tool for assessing the severity of symptoms and quality of life in patients with atrophic rhinitis. The internationally accepted SNOT-25 (Sino-Nasal Outcome Test-25) questionnaire with Houser’s modifications is used to assess the severity of symptoms of patients with empty nose syndrome and could be successfully applied for examination of patients with atrophic rhinitis. Research objectives. This research is aimed to evaluate the efficacy of the Russian nasal spray Olyfrin in the treatment of atrophic rhinitis. And also, to assess the possibility of using the SNOT 25 questionnaire with Houser’s modifications to determine symptom severity of atrophic rhinitis. Materials and Methods. At the first stage - validation of the SNOT-25 questionnaire modified by Houser - 64 patients were included in the study: 29 patients with atrophic rhinitis, 35 with other forms of chronic rhinitis. All patients filled in a prepared and adapted Russian-language version of the questionnaire. At the second stage - determination of the effectiveness of the spray Olyfrin in the treatment of atrophic rhinitis - the study included 29 patients with atrophic rhinitis. Olyfrin was used in 1 dose 3 times a day for 14 days. The dynamics of the severity of symptoms was assessed on the 7th and 14th days using the SNOT-25 questionnaire with Houser’s modifications. Analysis of the total number of points according to SNOT 25 with Houser’s modifications, along with the number of points scored for each of the questions, revealed a significant difference between the group of patients with atrophic rhinitis and the group of patients with other forms of chronic rhinitis (p <0.05). When studying the efficacy of the spray Olyfrin, statistically significant differences were found in the sum of points on the questionnaire before treatment and on the 7th day after treatment (p = 0.005), as well as before treatment and on the 14th day after treatment (p <0.001). A significant difference (p <0.05) was also obtained depending on the day of treatment with a decrease in the number of points of the severity of dryness in the nose (3.75 ± 1.55 vs 1.76 ± 1.43), sensation of excessive openness of the nose (0, 62 ± 0.26 vs 0.41 ± 0.14) and the formation of crusts in the nasal cavity (3.45 ± 1.37 vs 1.76 ± 0.87) already on the 7th day of treatment, and for all these symptoms with an additional decrease in the severity of the feeling of suffocation (1.14 ± 0.29 vs 0.28 ± 0.1) and difficulty in nasal breathing (1.62 ± 0.33 vs 0.45 ± 0.12) on the 14th day of treatment. Conclusions. According to our study, Olyfrin nasal spray is advisable to use when prescribing empirical therapy for patients with atrophic rhinitis. And to assess the quality of life and the dynamics of treatment of patients with atrophic rhinitis, the Russian-language version of the SNOT-25 questionnaire with Houser’s modifications can be successfully used.

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Section: ;19;4(107)unclassified

Evaluation of efficacy of the Olyfrin spray in treatment of patients with atrophic rhinitis using the Russian-language version of SNOT-25 questionnaire with Houser's modifications

Chuchueva¹,

Савлевич²,

Козлов³

et al. 2020

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The conchoplasty method in empty nose syndrome

Zargaryan¹,

Litvinov

2022

vmirvz

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The aim of the study is to reconstruct the resected inferior nasal cavity. A new method was developed and introduced, in which a spreader-implant in the form of a sandwich composite, which is a combination of a perforated plate of "Hi-Fatigue Bone Cement" of the required size, covered on one or both sides with the biocomposite material "LitAr", was used for the first time. As a result of the work, it was found that the "sandwich-implant" promotes cartilage and bone reparation, as well as mucosa of the lower nasal concha, stimulates neoangiogenesis and provides stability of the concha volume in the long term.

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Empty nose syndrome: A literature review

Cited by 2 publications

References 30 publications

Evaluation of efficacy of the Olyfrin spray in treatment of patients with atrophic rhinitis using the Russian-language version of SNOT-25 questionnaire with Houser's modifications

Evaluation of efficacy of the Olyfrin spray in treatment of patients with atrophic rhinitis using the Russian-language version of SNOT-25 questionnaire with Houser's modifications

The conchoplasty method in empty nose syndrome

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