Emulgel as a Novel Drug Delivery System: A Comprehensive Review

Joshi, Vaibhav; Kumar, Kapil; Khairya, Deepti; Teotia, Deepak

doi:10.46956/ijihd.v7i5.354

Cited by 2 publications

(2 citation statements)

References 6 publications

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“…Antioxidants are used in pharmaceutical formulations to enhance the chemical stability of drugs/components susceptible to oxidative destruction. The choice of antioxidants is determined by the kind of vehicle employed in the manufacture of the pharmaceutical dosage form; water-soluble antioxidants are the most common [39] .…”

Section: Antioxidantsmentioning

confidence: 99%

An overview of emulgels for topical application

Jabbar

Ali

2023

AJPS

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In recent years, gels have been preferentially used for cosmetics and topical pharmaceutical preparations due to their favorable characteristics, such as being greaseless, readily spreadable and easily removable. However, one obstacle that faced it was the inability to enclose hydrophobic compounds. Therefore, a novel approach was developed to circumvent this limitation by mixing the gel with an emulsion, which led to creation of a new topical drug delivery system known as emulgel. Emulgel preserves all favorable features of gel and provides also dual release for drug, thus can be utilized effectively in controlling release and absorption of medication after topical application. Emulgel preparation requires coherent steps, this includes preparation of emulsion and gel and determining their mixing ratio. Finally, the prepared emulgels should be evaluated to ensure their suitability and efficacy for the topical application.

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Section: Antioxidantsmentioning

confidence: 99%

An overview of emulgels for topical application

Jabbar

Ali

2023

AJPS

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“…They exhibit both fluid and semisolid properties, providing interesting possibilities for drug delivery and other applications. Emulgels can encapsulate both hydrophilic and lipophilic actives and provide controlled release [1]. They also demonstrate enhanced stability compared to emulsions alone.…”

Section: Introductionmentioning

confidence: 99%

The Expanding Scope of Emulgels: Formulation, Evaluation and Medical Uses

Kumar Sarella,

Pravallika

2023

ijcsrr

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Emulgels are semi-solid emulsions that combine the benefits of both emulsions and gels. They provide enhanced stability, sustained release and improved cosmetic properties. Emulgels can be fabricated using a variety of emulsification techniques and gelling agents like carbopol, hydroxypropyl cellulose. Characterization of emulgels includes evaluation of particle size, viscosity, pH, spreadability and drug release. Emulgels have promising applications in topical delivery of drugs and cosmetics, parenteral delivery of drugs and as emulsion-based oral drug delivery systems. Topical emulgels are used in skin care, hair care and cosmetics to provide moisturization, hydration, etc. Parenteral emulgels can deliver drugs in a sustained manner. Oral emulgels improve the absorption of some drugs. Several advantages of emulgels include sustained and controlled release of actives, improved solubility of both hydrophilic and lipophilic drugs, protection from degradation, and enhanced cosmetic elegance. However, emulgel formulation requires specialized emulsification equipment, and they have lower drug loading capacity compared to other semi-solid systems. Emulgels combine the benefits of emulsions and gels, providing a versatile drug and cosmetic delivery platform with unique advantages. Improvements in emulsification techniques, identifying newer gelling agents and permeation enhancers can further enhance the potential of emulgel systems. With growing research on emulgels, these systems are poised to make a significant impact on topical, parenteral and oral delivery in the coming years. Emulgels thus present an exciting prospect for developing innovative and improved formulations.

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Emulgel as a Novel Drug Delivery System: A Comprehensive Review

Cited by 2 publications

References 6 publications

An overview of emulgels for topical application

An overview of emulgels for topical application

The Expanding Scope of Emulgels: Formulation, Evaluation and Medical Uses

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