En-bloc resection of a giant cell tumor causing cervical vertebral collapse

Seddighi, Afsoun; Saied, Seddighi Amir; Nikouei, Amir; Javadian, Hamed

doi:10.4103/1793-5482.181136

Cited by 4 publications

(1 citation statement)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Spinal localization occurs more often in the sacrum [ 69 , 70 ], but it can also be found in the thoracic, lumbar [ 16 ] and cervical vertebrae [ 71 , 72 ]. The mass can also compress the spinal cord, producing neurological symptoms [ 73 ]. Vertebral localization is mainly in the vertebral body, but it can also involve posterior elements, especially in more aggressive cases [ 67 ].…”

Section: Giant Cell Tumor Of Bonementioning

confidence: 99%

Vertebra Plana: A Narrative Clinical and Imaging Overview among Possible Differential Diagnoses

et al. 2023

View full text Add to dashboard Cite

Vertebra plana is a rare radiologic condition characterized by a uniform loss of height of a vertebral body that represents a diagnostic challenge for surgeons. The purpose of this study was to review all possible differential diagnoses that may present with a vertebra plana (VP) described in the current literature. For that purpose, we performed a narrative literature review in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, analyzing 602 articles. Patient demographics, clinical presentation, imaging characteristics and diagnoses were investigated. VP is not a pathognomonic feature of Langerhans cell histiocytosis, but other oncologic and non-oncologic conditions should be considered. The list of differential diagnoses, based on our literature review, can be recalled with the mnemonic HEIGHT OF HOMO: H—Histiocytosis; E—Ewing’s sarcoma; I—Infection; G—Giant cell tumor; H—Hematologic neoplasms; T—Tuberculosis; O—Osteogenesis imperfecta; F—Fracture; H—Hemangioma; O—Osteoblastoma; M—Metastasis; O—Osteomyelitis, chronic.

show abstract

Section: Giant Cell Tumor Of Bonementioning

confidence: 99%

Vertebra Plana: A Narrative Clinical and Imaging Overview among Possible Differential Diagnoses

et al. 2023

View full text Add to dashboard Cite

show abstract

Unraveling the mystery: A comprehensive review of multidisciplinary strategies for managing giant cell tumor of the bone

Abbasi,

Qamar,

Habib

et al. 2025

Journal of Orthopaedic Reports

View full text Add to dashboard Cite

Imaging Features of Aggressive Giant Cell Tumors of the Mobile Spine: Retrospective Analysis of 101 Patients From Single Center

Yuan

Zhang

Yang

et al. 2021

Global Spine Journal

View full text Add to dashboard Cite

Study Design: Retrospective study. Objectives: Giant cell tumors (GCTs) of the mobile spine can be locally aggressive. This study described and classified the typical and atypical appearance of aggressive spinal GCTs according to imaging findings to help the imaging diagnosis, especially for patients with rapid neurological deficit that may require emergent surgery without biopsy. Methods: Computed tomography (CT) and magnetic resonance imaging (MRI) scans of patients diagnosed with aggressive spinal GCTs at single center were reviewed. Results: Overall, 101 patients with 100 CT images and 94 MR images were examined. All lesions were osteolytic with cortical destruction; 95 lesions showed epidural extension; 90 were centered in the vertebral body; 82 showed pathological fracture and/or collapse of the vertebral body; 78 had pseudotrabeculation on CT; 80 showed low-to-iso signal intensity or heterogeneous high-signal intensity with cystic areas on the T2-weighted images; 9 showed fluid–fluid level on T2-weighted images; and 61 patients showed marked enhancement on contrast-enhanced CT and/or MRI. Forty-one lesions (40.6%) had at least 1 atypical radiographic feature: 19 involved ≥2 segments; 11 were centered in the posterior neural arch; 10 had a paravertebral mass over 2 segments; 16 showed partial margin sclerosis with partial cortical destruction on CT scans; and 3 showed mineralization within the tumor on CT. Eighty-eight patients underwent CT-guided biopsy with a diagnostic accuracy rate of 94.3%. Conclusions: Spinal GCTs might appear more radiologically atypical, and about 40% of the lesions may have at least 1 atypical feature. CT-guided biopsies are recommended for definitive diagnosis.

show abstract

En-bloc resection of a giant cell tumor causing cervical vertebral collapse

Cited by 4 publications

References 20 publications

Vertebra Plana: A Narrative Clinical and Imaging Overview among Possible Differential Diagnoses

Vertebra Plana: A Narrative Clinical and Imaging Overview among Possible Differential Diagnoses

Unraveling the mystery: A comprehensive review of multidisciplinary strategies for managing giant cell tumor of the bone

Imaging Features of Aggressive Giant Cell Tumors of the Mobile Spine: Retrospective Analysis of 101 Patients From Single Center

Contact Info

Product

Resources

About