En Bloc Resection of Supraglottic Carcinomas with Transoral Laser Microsurgery

Abstract

Objective: Complete en bloc supraglottic tumor excision with transoral laser microsurgery (TLM) can be achieved with good postoperative outcomes. We report surgical feasibility and the postsurgical outcomes of en bloc resection of supraglottic laryngeal squamous cell carcinomas (LSCC) with TLM. Methods: Seventeen patients who underwent TLM for supraglottic laryngeal cancer were included in the study. Demographic and pathological data, clinic and follow-up outcomes of the patients were reviewed and analyzed. Results: Type 1 TLM was performed in three patients, type 2a in one patient, type 3b in 12 patients, and type 4b in one patient. Negative surgical margins were achieved in all of the cases. Re-excision or any adjuvant treatment for positive resection margins was not required in any of the cases. Eight patients received adjuvant radiotherapy due to lymph node metastasis. Mean follow-up time was 33.8±15.7 months (range: 10–65 months). None of the patients had recurrence or distant metastasis. Conclusion: The transoral approach with the use of CO 2 laser and microscopy offers complete tumor excision for treating supraglottic LSCC. The three-dimensional structure of the supraglottis can be achieved with adequate exposure. En bloc resection is possible with safe margins.

Expression and clinical significance of FGFR1 and FGFR2 in laryngeal squamous cell carcinoma

“…Surgery remains the most effective treatment, and the application of CO 2 laser cautery is widely popular at home and abroad because of its advantages of small trauma and quick recovery. This method is not only widely used in the treatment of glottic laryngeal cancer ( 5 ), but also in the treatment of supraglottic laryngeal cancer ( 6 ). Adjuvant chemoradiotherapy and postoperative rehabilitation treatment are also indispensable, and it is worth mentioning that an increasing number of a study show postoperative psychosocial factors in patients with advanced laryngeal cancer such as family support, communication, language clarity, and work and family relationships all help to improve postoperative survival ( 7 ).…”