Abstract-Scientificworkflow management systems (SWFMSs) are facing unprecedented challenges from big data deluge. As revising all the existing workflow applications to fit into Cloud computing paradigm is impractical, thus migrating SWFMSs into the Cloud to leverage the functionalities of both Cloud computing and SWFMSs may provide a viable approach to big data processing. In this paper, we first discuss the challenges for scientific workflow applications and the available solutions in details, and analyze the essential requirements for a scientific computing Cloud platform. Then we propose a service framework to normalize the integration of SWFMS with Cloud computing. Meanwhile, we also present our implementation experience based on the service Framework. At last, we set up a series of experiments to demonstrate the capability of our implementation and use a Montage Image Mosaic Workflow as a showcase of the implementation.