Enamel Demineralization by Mouthrinses Containing Different Concentrations of Sucrose

Tehrani, Ashraf Mazaheri; Brudevold, F.; Attarzadeh, F.; Houte, J. van; Russo, Juliana do Espírito Santo

doi:10.1177/00220345830620120801

Cited by 10 publications

(5 citation statements)

References 6 publications

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“…These results are consistent with a recent finding involving the intraoral demineralization test which showed that demineralization is a function of total sugar exposure [Tehrani et al, 1983]. 2 rinses with a 5% solution caused demineralization; 6 rinses were needed with a 1 % solution, 9 rinses with 0.5%, and no demineralization was ob served with 9 rinses of an 0.3% solution.…”

Section: Discussionsupporting

confidence: 92%

Salivary Glucose Clearance after Rinsing with Solutions of Different Concentrations of Glucose

Goulet¹,

Brudevold²

1984

Caries Res

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The rate of salivary glucose clearance was determined in 6 subjects after rinsing with solutions ranging in concentration from 0.3 to 50%. 6 repeated rinses of 10% glucose by 1 subject gave clearance times, i.e. time to reach 10 mg%, ranging from 18.7 to 24.6 min, while the clearance time of single rinses by each of the subjects ranged from 13.6 to 23.3 min. The coefficients of variation were 9.8 and 21.7%. Plotting the logarithm of the saliva concentrations of glucose against time gave linear curves (r close to ––1), with slopes which decreased with increase in rinse concentration. The mean half-time, i.e. the time required for a given concentration to reach half its value, was 0.8 min for the 0.3% rinse, increasing to 2.8 min for the 50% rinse. The time of clearance from the initial concentration to a baseline value of 10 mg% increased linearly with the logarithm of the rinse concentrations, and ranged from a mean of 3.2 min for the 0.3% rinse to a mean of 27.5 min for the 50% rinse. There was considerable between-subject variation in the rate of clearance, the rate for a given subject being consistently slow or consistently fast for all rinse concentrations.

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Section: Discussionsupporting

confidence: 92%

Salivary Glucose Clearance after Rinsing with Solutions of Different Concentrations of Glucose

Goulet¹,

Brudevold²

1984

Caries Res

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“…Treatment with 5% sucrose solution resulted in similar mineral loss as in 10 and 20% sucrose treatments and enamel demineralization was observed in dental blocks treated with 5% sucrose solution, in agreement with Tehrani et al [1983]. However, unlike the present work, Tehrani et al [1983] did not compare 5% sucrose solution with higher sucrose concentrations.…”

Section: Discussionsupporting

confidence: 86%

“…In a short-term study, using artifi cial biofi lm, Tehrani et al [1983] found that two rinses with 1% sucrose solution did not result in mineral loss, which was, however, observed when 5% sucrose solution was utilized.…”

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confidence: 99%

Effect of Sucrose Concentration on Dental Biofilm Formed in situ and on Enamel Demineralization

et al. 2005

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The relationship between sucrose concentration and cariogenic potential was studied in situ. Adult volunteers wore intraoral palatal appliances containing human dental enamel blocks, which were extraorally submitted 8 times a day for 14 days, to the treatments: deionized distilled water and sucrose solutions from 1 to 40%. The biofilm formed was analyzed with respect to acidogenicity and biochemical composition; enamel demineralization was evaluated by microhardness. The results showed that 1% sucrose is less cariogenic than 5% or higher concentrations, although sucrose solution at 40% was still able to increase the concentration of insoluble polysaccharide in the biofilm formed. The findings suggest that the threshold of sucrose solution concentration for the formation of a cariogenic biofilm is 5%, which provided the same cariogenic potential as that observed for 10 and 20% sucrose solution.

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“…However, previous data from an in situ study have shown a statistically significant increase in mineral loss of enamel slabs exposed to 5% sucrose compared with those exposed to 1% sucrose [27]. The same trend was also observed by a short-term study using artificial biofilm [28]. The differences found between our data and those of Aires et al [27] might be related mainly to the fact that in the latter study sucrose was provided to the in situ formed biofilms in a frequency of 8x/day during 14 days whereas the cariogenic challenge in our study was induced only three times a day during 5 days only.…”

Section: Discussionsupporting

confidence: 67%

Enamel Carious Lesion Development in Response to Sucrose and Fluoride Concentrations and to Time of Biofilm Formation: An Artificial-Mouth Study

Arthur

Kohara

Waeiss

et al. 2014

Journal of Oral Diseases

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The aim of this study was to evaluate both sucrose and fluoride concentrations and time of biofilm formation on enamel carious lesions induced by an in vitro artificial-mouth caries model. For Study 1, biofilms formed by streptococci and lactobacilli were grown on the surface of human enamel slabs and exposed to artificial saliva containing 0.50 or 0.75 ppmF (22.5 h/d) and broth containing 3 or 5% sucrose (30 min; 3x/d) over 5 d. In Study 2, biofilms were grown in the presence of 0.75 ppmF and 3% sucrose over 3 and 9 days. Counts of viable cells on biofilms, lesion depth (LD), and the integrated mineral loss (IML) on enamel specimens were assessed at the end of the tested conditions. Counts of total viable cells and L. casei were affected by sucrose and fluoride concentrations as well as by time of biofilm formation. Enamel carious lesions were shallower and IML was lower in the presence of 0.75 ppmF than in the presence of 0.50 ppmF (P < 0.005). No significant effect of sucrose concentrations was found with respect to LD and IML (P > 0.25). Additionally, deeper lesions and higher IML were found after 9 d of biofilm formation (P < 0.005). Distinct sucrose concentrations did not affect enamel carious lesion development. The severity of enamel demineralization was reduced by the presence of the higher fluoride concentration. Additionally, an increase in the time of biofilm formation produced greater demineralization. Our results also suggest that the present model is suitable for studying aspects related to caries lesion development.

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Enamel Demineralization by Mouthrinses Containing Different Concentrations of Sucrose

Cited by 10 publications

References 6 publications

Salivary Glucose Clearance after Rinsing with Solutions of Different Concentrations of Glucose

Salivary Glucose Clearance after Rinsing with Solutions of Different Concentrations of Glucose

Effect of Sucrose Concentration on Dental Biofilm Formed in situ and on Enamel Demineralization

Enamel Carious Lesion Development in Response to Sucrose and Fluoride Concentrations and to Time of Biofilm Formation: An Artificial-Mouth Study

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