Enantio- and diastereoselective boron conjugate addition to α-alkyl α,β-unsaturated esters

Abstract

We developed a copper-catalyzed enantio- and diastereoselective boron conjugate addition to α‑alkyl α,β-unsaturated esters under base-free conditions. The approach showed excellent enantioselectivities (87~99% ee) and moderate to good conversions (51~99%),...