Enantiomeric composition of abused amine drugs: chromatographic methods of analysis and data interpretation

Enantiomeric determination of ephedrines and norephedrines by chiral derivatization gas chromatography–mass spectrometry approaches

“…Enantiomeric analysis of amphetamine-related drug has recent been reviewed [18]. There have been a few studies specifically related to epherdines [15,19,20], norephedrines [21,22], and cathine [21,22].…”

High‐Performance Liquid Chromatographic Analysis of Psychotropic and Endogenous Compounds

“…These phases include molecularly imprinted polymers, cyclodextrins, and crown-ether. Proton donor and proton acceptor type stationary phases make up another category that includes Pirkle type and low-molecular weight CSPs (Liu and Liu, 2002).…”

“…A transient diastereomeric complex is formed between the enantiomer and the chiral component in the mobile phase, similar to the complexes formed with chiral stationary phases. A review by Liu and Liu (2002) cites several papers where addition of CPMAs has been used in analyzing amphetamine-related compounds. Some CPMAs include amino acid enantiomers, metal ions, proteins, and cyclodextrins.…”

Stereoselective Inhibition of Renal Basolateral Human Organic Anion Transporter 3 by Lansoprazole Enantiomers

“…Since some chiral compounds have different pharmacokinetics and pharmacodynamics between enantiomers [17, 18], the development of single-enantiomer drugs is encouraged by the guidelines for the development of chiral drugs worldwide [17, 19]. By using recent advances in separation technology of single enantiomers from previously marketed racemic PPIs [20], (R)-lansoprazole and (S)-omeprazole have been developed as ethical drugs, which are called dexlansoprazole and esomeprazole respectively [21-23].…”