Abstract:A large number of chiral drug molecules have a chiral structure containing both D-and L-enantiomers, leading to the mirror image arrangements of the two forms eliciting quite different physiological responses. Penicillamine (Pen) is a common chiral drug that is obtained from penicillin, and researchers have been making continuous efforts to achieve rigorous analysis and discrimination of the two enantiomers. Based on chiral Schiff base macrocycles containing NH functionalities have the advantages of mild synth… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.