Enantiometric Separation of Sitagliptin in a Fixed Dose Combination Formula of Sitagliptin and Metformin by a Chiral Liquid Chromatographic Method

Jaishetty, Nagadeep; Kamaraj, P.; Maruthapillai, Arthanareeswari

doi:10.22159/ijpps.2019v11i6.22699

Cited by 4 publications

(4 citation statements)

References 16 publications

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“…HTC-3003, Andheri (E), Mumbai, India). Physical observation of the blend was recorded at initial, 2 and 4 w for two months [4]. Physical characteristics (colour change) were checked on a regular basis.…”

Section: Construction Of Calibration Curvementioning

confidence: 99%

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Comparative Study of Semi-Solid Bases of Naproxen: Pharmaceutical Technology Aspects

SRIVIDYA¹,

NACHIYA

Ebrahim

et al. 2022

Int J App Pharm

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Objective: The main objectives of the present investigation work included that the preparation of a suitable naproxen semi-solid dosage form by using different types of semi-solid bases (gel bases, ointment bases) for topical application for the effective treatment of muscle aches. Methods: Different types of semi-solid bases (gel bases and ointment bases) were successfully prepared by the incorporation method to know the effect of semi-solid bases on drug release from topical semi-solid formulations. In all formulations, the drug was added by the levigation method. An evaluation study of prepared formulations, includes physical appearance, spreadability, extrudability, pH was conducted according to official methods. Results: Percent drug release of all formulations was conducted by taking diffusion cells with cellophane membrane and results showed that gel-based formulations showed more drug release than ointment-based formulations. Carbopol gel base (F1) showed more drug release (98.76 %), simple ointment base formulation (F8) showed least drug release (25.11%). From the stability studies reports at various temperature and humidity conditions it is evident that all formulations are stable for one month. In all the formulations, the drug content was observed at 95.75%. Conclusion: Finally concluded that the NXN topical dosage forms can be prepared by using gel-type bases preferably than ointment bases to release more drug from formulations.

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Section: Construction Of Calibration Curvementioning

confidence: 99%

“…The proportions as mentioned in table 1 are accurately weighed and compounding was done by the method of incorporation as per the previous study performed by Kameswararao et al [4]. The stainless steel spatula and porcelain tile were used for levigation.…”

Section: Formulation Of Nxn Semisolid Basesmentioning

confidence: 99%

Comparative Study of Semi-Solid Bases of Naproxen: Pharmaceutical Technology Aspects

SRIVIDYA¹,

NACHIYA

Ebrahim

et al. 2022

Int J App Pharm

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“…Increased Ag2O NPs matrix reduced average particle size. Formation of Ag-O-Ag on doped nanoparticle surfaces prevented crystal grain growth and particle separation, reducing particle size (Jaishetty et al, 2016;Nagadeep et al, 2019;Jaishetty et al, 2019).…”

Section: Sem Exammentioning

confidence: 99%

Green Synthesis of Silver Oxide Nanoparticles by using Clerodendrum bracteatum Leaf Extract and Their Antibacterial Activity

I.¹,

R.²,

P.³

et al. 2022

IJZI

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Plant-mediated nanoparticle production is fast, simple, environmentally friendly, and inexpensive. This study synthesised silver nanoparticles using Clerodendrum bracteatum leaf extract. FT-IR, SEM, XRD, and Zeta potential were used to characterise silver nanoparticles. FT-IR was utilised to determine the functional groups responsible for reducing silver nitrate and capping agents in the leaf extract. Using Zeta potential, silver nanoparticles' stability was measured. Silver nanoparticles' 18.3 mV negative Zeta potential showed durability. Silver nanoparticles show antibacterial action against Staphylococcus aureus, Microc

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“…Hibiscus (Hibiscus rosa sinensis, Malvaceae) is helps in hair growth, soft and glossiness. The red flowered variety is preferred in medicine [8].…”

Section: Introductionmentioning

confidence: 99%

Studies on Poly Herbal Powder Shampoo for the Treatment of Pediculosis Capitis and Pityriasis Capitis Infestations

MOHAMED¹,

Elhassan

Khan

et al. 2022

Int J App Pharm

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Objective: The main objective of this study was to the formulation containing polyherbal medicinal plants, which gives safety, and efficacy; rectify skin disease, scalp disorders and reducing the harmful effect from herbal anti-lice and dandruff shampoos for the treatment of Pediculosis capitis and Pityriasis capitis and to prevent hair fall. Methods: The formulation of herbal shampoo with various herbal ingredients were dried, milled, sieved (120#) and mixed in geometrical order and evaluated their physicochemical characteristics. Furthermore, particle characters, organoleptic properties, foaming index, skin irritation study, and Anti-lice activity were performed. Results: The prepared poly herbal powdered shampoo (PHPS) exhibits that was freely soluble, particle 20-25 μm size range and free-flowing powder. Lest moisture content (2.5%), ash value, acid value and reduced surface tension of liquid are referred as an ideal candidate for foaming, anti-lice potential with no skin irritations. Conclusion: Based on the evaluation parameters, the prepared powdered shampoo helps to remove hair grease, no hair fall and strengthen hair follicles. Preparation of PHPS formulation at laboratory scale and the compounding of several ingredients of herbal source have produced it possible to ensure safety, efficacy and secure highly effective PHPS.

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Enantiometric Separation of Sitagliptin in a Fixed Dose Combination Formula of Sitagliptin and Metformin by a Chiral Liquid Chromatographic Method

Cited by 4 publications

References 16 publications

Comparative Study of Semi-Solid Bases of Naproxen: Pharmaceutical Technology Aspects

Comparative Study of Semi-Solid Bases of Naproxen: Pharmaceutical Technology Aspects

Green Synthesis of Silver Oxide Nanoparticles by using Clerodendrum bracteatum Leaf Extract and Their Antibacterial Activity

Studies on Poly Herbal Powder Shampoo for the Treatment of Pediculosis Capitis and Pityriasis Capitis Infestations

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