1,2,3-Triazole scaffolds
are not obtained in nature, but they are
still intensely investigated by synthetic chemists in various fields
due to their excellent properties and green synthetic routes. This
review will provide a library of all synthetic routes used in the
past 21 years to synthesize 1,2,3-triazoles and their derivatives
using various metal catalysts (such as Cu, Ni, Ru, Ir, Rh, Pd, Au,
Ag, Zn, and Sm), organocatalysts, metal-free as well as solvent- and
catalyst-free neat syntheses, along with their mechanistic cycles,
recyclability studies, solvent systems, and reaction condition effects
on regioselectivity. Constant developments indicate that 1,2,3-triazoles
will help lead to future organic synthesis and are useful for creating
molecular libraries of various functionalized 1,2,3-triazoles.