Encapsulation of Fatty Oils into Electrospun Nanofibers for Cosmetic Products with Antioxidant Activity

Miletić, Aleksandra; Pavlić, Branimir; Ristić, Ivan; Zeković, Zoran; Pilić, Branka

doi:10.3390/app9152955

Cited by 23 publications

(18 citation statements)

References 22 publications

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“…Similarly, PLA and PLGA-based scaffolds’ low mechanical properties resulted in their permanent deformation after a prolonged duration of cyclic strain [ 4 ]. On the other hand, the flexible mechanical proprieties of PCL-based nanofiber membranes resulted in their extensive study in various applications [ 5 ].…”

Section: Mechanical Properties Of Electrospun Nf Implantsmentioning

confidence: 99%

“…The ultrathin NFs have multiple applications in various fields [ 4 ], such as cosmetics [ 5 ], active food packaging [ 6 ], fabricated fabricating nanofibrous sensors [ 7 ], textiles [ 8 ], and in particular, their applications in drug delivery [ 9 , 10 , 11 ], wound healing [ 12 , 13 ], nanomedicine and tissue engineering [ 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

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Electrospun Nanofibers Revisited: An Update on the Emerging Applications in Nanomedicine

et al. 2022

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Electrospinning (ES) has become a straightforward and customizable drug delivery technique for fabricating drug-loaded nanofibers (NFs) using various biodegradable and non-biodegradable polymers. One of NF's pros is to provide a controlled drug release through managing the NF structure by changing the spinneret type and nature of the used polymer. Electrospun NFs are employed as implants in several applications including, cancer therapy, microbial infections, and regenerative medicine. These implants facilitate a unique local delivery of chemotherapy because of their high loading capability, wide surface area, and cost-effectiveness. Multi-drug combination, magnetic, thermal, and gene therapies are promising strategies for improving chemotherapeutic efficiency. In addition, implants are recognized as an effective antimicrobial drug delivery system overriding drawbacks of traditional antibiotic administration routes such as their bioavailability and dosage levels. Recently, a sophisticated strategy has emerged for wound healing by producing biomimetic nanofibrous materials with clinically relevant properties and desirable loading capability with regenerative agents. Electrospun NFs have proposed unique solutions, including pelvic organ prolapse treatment, viable alternatives to surgical operations, and dental tissue regeneration. Conventional ES setups include difficult-assembled mega-sized equipment producing bulky matrices with inadequate stability and storage. Lately, there has become an increasing need for portable ES devices using completely available off-shelf materials to yield highly-efficient NFs for dressing wounds and rapid hemostasis. This review covers recent updates on electrospun NFs in nanomedicine applications. ES of biopolymers and drugs is discussed regarding their current scope and future outlook.

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Section: Mechanical Properties Of Electrospun Nf Implantsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Electrospun Nanofibers Revisited: An Update on the Emerging Applications in Nanomedicine

et al. 2022

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“…Conversely, loaded onto gelatin, caffeic acid showed poor activity regarding phenolic compounds; thus, caffeic acid antioxidant activity depends on its interaction with the nanofiber surface. PLA and PVP were used by Miletić et al [97] to load pomegranate seed oil (PSO), ethanolic extract of fermented pomegranate juice (EP), and cold-pressed sea-buckthorn oil (SB) (separately). Pomegranates (as berries) have been traditionally used due to their antioxidant and anti-inflammatory properties.…”

Section: Othersmentioning

confidence: 99%

Applications of Electrospun Nanofibers with Antioxidant Properties: A Review

et al. 2020

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Antioxidants can be encapsulated to enhance their solubility or bioavailability or to protect them from external factors. Electrospinning has proven to be an excellent option for applications in nanotechnology, as electrospun nanofibers can provide the necessary environment for antioxidant encapsulation. Forty-nine papers related to antioxidants loaded onto electrospun nanofibers were categorized and reviewed to identify applications and new trends. Medical and food fields were commonly proposed for the newly obtained composites. Among the polymers used as a matrix for the electrospinning process, synthetic poly (lactic acid) and polycaprolactone were the most widely used. In addition, natural compounds and extracts were identified as antioxidants that help to inhibit free radical and oxidative damage in tissues and foods. The most recurrent active compounds used were tannic acid (polyphenol), quercetin (flavonoid), curcumin (polyphenol), and vitamin B6 (pyridoxine). The incorporation of active compounds in nanofibers often improves their bioavailability, giving them increased stability, changing the mechanical properties of polymers, enhancing nanofiber biocompatibility, and offering novel properties for the required field. Although most of the polymers used were synthetic, natural polymers such as silk fibroin, chitosan, cellulose, pullulan, polyhydroxybutyrate, and zein have proven to be proper matrices for this purpose.

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“…This material is trending in textile-based research where different researchers are working to manufacture smart textiles to generate energy [ 22 – 23 ]. Nanofibers have many technical applications such as in air and liquid filtration [ 24 – 25 ], tissue engineering [ 26 – 27 ], drug delivery [ 28 ], wound dressings [ 29 ], sound adsorption [ 30 ], cosmetics [ 31 ], and sensor devices [ 32 – 34 ]. In filtration processes, electrospun nanofibers can be employed for removing volatile organic compounds (VOCs) from the atmosphere.…”

Section: Introductionmentioning

confidence: 99%

Piezoelectric nanogenerator for bio-mechanical strain measurement

Javed¹,

Rafiq²,

Nazeer³

et al. 2022

Beilstein J. Nanotechnol.

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Piezoelectric materials have attracted more attention than other materials in the field of textiles. Piezoelectric materials offer advantages as transducers, sensors, and energy-harvesting devices. Commonly, ceramics and quartz are used in such applications. However, polymeric piezoelectric materials have the advantage that they can be converted into any shape and size. In smart textiles, polyvinylidene fluoride (PVDF) and other piezoelectric polymers are used in the form of fibers, filaments, and composites. In this research, PVDF nanofibers were developed and integrated onto a knitted fabric to fabricate a piezoelectric device for human body angle monitoring. Scanning electron microscopy and X-ray diffraction analyses were used to study the morphology and to confirm the beta phase in fibers. The results reveal that the nanofibers made from solutions with high concentration were smooth and defect-free, compared to the fibers obtained from solutions with low concentration, and possess high crystallinity as well. Under high dynamic strain more output voltage is generated than under low dynamic strain. The maximum current density shown by the device is 172.5 nA/cm2. The developed piezoelectric nanofiber sensor was then integrated into a knitted fabric through stitching to be used for angle measurement. With increasing bending angle, the output voltage increased. The promising results show that the textile-based piezoelectric sensor developed in this study has a great potential to be used as an angle measuring wearable device for the human body due to its high current density output and flexibility.

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Encapsulation of Fatty Oils into Electrospun Nanofibers for Cosmetic Products with Antioxidant Activity

Cited by 23 publications

References 22 publications

Electrospun Nanofibers Revisited: An Update on the Emerging Applications in Nanomedicine

Electrospun Nanofibers Revisited: An Update on the Emerging Applications in Nanomedicine

Applications of Electrospun Nanofibers with Antioxidant Properties: A Review

Piezoelectric nanogenerator for bio-mechanical strain measurement

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