Encapsulation of lycopene into electrospun nanofibers from whey protein isolate-Tricholoma lobayense polysaccharide complex stabilized emulsions: Structural characterization, storage stability, in vitro release, and cellular evaluation

Chen, Lei; Xiang, Ming; Wu, Fen; Jiang, Yun; Wu, Qing-Xi; Zhang, Wenna; Guo, Wenzhong; Cai, Bolin; Liang, Li; Li, Songnan; Chen, Yan; Du, Xianfeng

doi:10.1016/j.ijbiomac.2023.123993

Cited by 21 publications

(2 citation statements)

References 57 publications

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“…These findings stand in accordance with other emulsion electrospinning studies, where, for example, adding bovine serum albumin into the aqueous phase increased conductivity and elongated the polymer jet to result in thinner fibers compared with the pure polymer fibers (no aqueous phase) [ 37 ]. On average, thinner fibers were also obtained via increasing the percentage of water in a water-in-oil electrospinning study [ 38 ].…”

Section: Discussionmentioning

confidence: 99%

Bioactive and Elastic Emulsion Electrospun DegraPol Tubes Delivering IGF-1 for Tendon Rupture Repair

Rieber

Meier-Bürgisser

Miescher

et al. 2023

IJMS

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Tendon injuries can result in two major drawbacks. Adhesions to the surrounding tissue may limit the range of motion, while fibrovascular scar formation can lead to poor biomechanical outcomes. Prosthetic devices may help to mitigate those problems. Emulsion electrospinning was used to develop a novel three-layer tube based on the polymer DegraPol (DP), with incorporated insulin-like growth factor-1 (IGF-1) in the middle layer. Scanning electron microscopy was utilized to assess the fiber diameter in IGF-1 containing pure DP meshes. Further characterization was performed with Fourier Transformed Infrared Spectroscopy, Differential Scanning Calorimetry, and water contact angle, as well as through the assessment of mechanical properties and release kinetics from ELISA, and the bioactivity of IGF-1 by qPCR of collagen I, ki67, and tenomodulin in rabbit Achilles tenocytes. The IGF-1-containing tubes exhibited a sustained release of the growth factor up to 4 days and showed bioactivity by significantly upregulated ki67 and tenomodulin gene expression. Moreover, they proved to be mechanically superior to pure DP tubes (significantly higher fracture strain, failure stress, and elastic modulus). The novel three-layer tubes intended to be applied over conventionally sutured tendons after a rupture may help accelerate the healing process. The release of IGF-1 stimulates proliferation and matrix synthesis of cells at the repair site. In addition, adhesion formation to surrounding tissue can be reduced due to the physical barrier.

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Section: Discussionmentioning

confidence: 99%

Bioactive and Elastic Emulsion Electrospun DegraPol Tubes Delivering IGF-1 for Tendon Rupture Repair

Rieber

Meier-Bürgisser

Miescher

et al. 2023

IJMS

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“…In recent years, emulsion electrospinning has been rapidly developing to be an alternative technique of conventional electrospinning. With the rapid growth of new materials from renewable resources, diverse wall materials are appropriate for emulsion electrospinning, including biopolymers [ 15 , 16 , 17 ] (e.g., proteins, polysaccharides) and biocompatible polymers (e.g., poly vinyl alcohol (PVA [ 18 ]), polyethylene oxide (PEO) [ 19 ], polycaprolactone (PCL) [ 20 ]). They can be used individually or in combination according to the type and specific usages of the food ingredients.…”

Section: Introductionmentioning

confidence: 99%

Improvement of Stress Resistance of Microencapsulated Lactobacillus plantarum by Emulsion Electrospinning

Wu,

Zhang,

Yan

et al. 2024

Foods

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Probiotics have become increasingly recognized for their potential health-promoting properties; however, the viability of probiotics can be affected by storage and transportation processes as well as the stressful environment of the human digestive tract, preventing them from achieving effective concentration (107 CFU/mL). In this regard, the embedding technology of probiotics provides an effective protection method. Dextran-based water in water (W/W) emulsion loaded with Lactobacillus plantarum was used as spinning solution to prepare Lactobacillus plantarum-loaded electrospun fibers. The structure of the W/W emulsion and the electrospun fibers was charactered. Lactobacillus plantarum were uniformly embedded in the internal phase of the W/W emulsion and the loading efficiency was 9.70 ± 0.40 log CFU/g. After 240 min digestion in the gastrointestinal tract, and temperature treatment in 65 °C and 72 °C, the loaded probiotics maintained high activity. Even after 5 days of storage in room temperature and 4 °C, the loaded probiotic activity levels remained high, with counts >8 log CFU/g. These results suggest that probiotics encapsulated by emulsion electrospinning could be potentially delivered in a novel food delivery system used in the future food industry.

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Needleless Electrospinning: Concepts and Applications in the Food Industry

Raja,

Mahalakshmi,

Leena

et al. 2023

Food Eng Rev

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Encapsulation of lycopene into electrospun nanofibers from whey protein isolate-Tricholoma lobayense polysaccharide complex stabilized emulsions: Structural characterization, storage stability, in vitro release, and cellular evaluation

Cited by 21 publications

References 57 publications

Bioactive and Elastic Emulsion Electrospun DegraPol Tubes Delivering IGF-1 for Tendon Rupture Repair

Bioactive and Elastic Emulsion Electrospun DegraPol Tubes Delivering IGF-1 for Tendon Rupture Repair

Improvement of Stress Resistance of Microencapsulated Lactobacillus plantarum by Emulsion Electrospinning

Needleless Electrospinning: Concepts and Applications in the Food Industry

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