Encapsulation of Triphenylene Derivatives in the Hexanuclear Arene Ruthenium Metallo‐Prismatic Cage [Ru₆(p‐PrⁱC₆H₄Me)₆(tpt)₂(dhbq)₃]⁶⁺ (tpt = 2,4,6‐tri(pyridin‐4‐yl)‐1,3,5‐triazine, dhbq = 2,5‐dihydroxy‐1,4‐benzoquinonato)

Abstract

Abstract.A large cationic triangular metallo-prism, [Ru 6 (pPr i C 6 H 4 Me) 6 (tpt) 2 (dhbq) 3 ] 6ϩ (1) 6ϩ , incorporating p-cymene ruthenium building blocks, bridged by 2,5-dihydroxy-1,4-benzoquinonato (dhbq) ligands, and connected by two 2,4,6-tri(pyridin-4-yl)-1,3,5-triazine (tpt) subunits, allows the permanent encapsulation of the triphenylene derivatives hexahydroxytriphenylene, C 18 H 6 (OH) 6 and hexamethoxytriphenylene, C 18 H 6 (OMe) 6 . These two cationic carceplex systems [C 18 H 6 (OH) 6 ʚ1] 6ϩ and

Synthesis, Characterisation and In Vitro Anticancer Activity of Hexanuclear Thiolato‐Bridged Arene Ruthenium Metalla‐Prisms

“…One‐dimensional ROESY experiments : 1D selective 1 H ROESY experiments were recorded by using the GROESY pulse sequence,15 which has been shown to be effective for measuring distances in similar compounds 16. The mixing time of the experiments was deliberately kept short (100 ms) to avoid spin diffusion and so that the linear approximation remained valid 17.…”

Arene Ruthenium Cages: Boxes Full of Surprises

“…[32] Indeed, these systems have allowed the permanent encapsulation of large aromatic molecules such as pyrene (C 16 H 10 ), fluoranthene (C 16 H 10 ), triphenylene (C 18 H 12 ), benzo[e]pyrene (C 20 H 12 ) and coronene (C 24 H 12 ), [33] or the encapsulation of functionalised triphenylene molecules hexahydroxytriphenylene [C 18 H 6 (OH) 6 ] and hexamethoxytriphenylene [C 18 H 6 (OMe) 6 ]. [34] The structures of [C 16 H 10 ʚ17b]-(CF 3 SO 3 ) 6 and [C 20 H 12 ʚ17b](CF 3 SO 3 ) 6 , obtained by single-crystal X-ray structural analysis, are presented in Figure 10. However, despite the presence of these large aromatic molecules (pyrene and benzo[e]pyrene) in the cavity of 17b, the staggered conformation of the two 4-tpt units remains, thus conserving the chirality of the metalla-prism 17b.…”

“…[33] Single-crystal X-ray structural analysis of the carceplex system [C 18 H 6 (OMe) 6 ʚ17b](CF 3 SO 3 ) 6 has been performed as well. [34] Because of its size and the presence of six methoxy groups, the hexamethoxytriphenylene is strongly encapsulated in 17b, and the twists of the two 4-tpt units, as well as the rotation of the pyridyl groups, are locked in this system (see Figure 11). Therefore, this system shows no chirality in the solid state and crystallises in the trigonal space group R3c.…”

“…Molecular structure of [C 18 H 6 (OMe) 6 ʚ17b](CF 3 -SO 3 ) 6 . [34] single-crystal X-ray structural analysis (see Figure 12). The Pt(acac) 2 complex is strongly held between the triazine units of the 4-tpt ligands, the platinum triazine···centroid separation being 3.4 Å.…”

Anticancer Activity of Half‐Sandwich RhIII and IrIII Metalla‐Prisms Containing Lipophilic Side Chains

“…These values were in agreement with the RuÀRu distance (7.857(1) ) and the triazine-triazine separation (6.6 ) observed in the metalla-prism [(h 6 -C 10 H 14 ) 6 Ru 6 (m 3 -tpt-kN) 2 (m 4 -C 6 H 2 O 4 -kO) 3 ] 6 + in which the cavity is occupied by a planar hexamethoxytriphenylene molecule. [12] In the crystal packing of [3][CF 3 SO 3 ] 6 two molecules of benzene were observed. These benzene molecules together with the triflate anions filled the voids left between the hexanuclear metalla-prisms.…”