Encapsulation of water-insoluble polyphenols and β-carotene in Ca-alginate microgel particles produced by the Leeds Jet Homogenizer

Pravinata, Linda C.; Murray, Brent S.

doi:10.1016/j.colsurfa.2018.10.041

Cited by 13 publications

(3 citation statements)

References 26 publications

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“…Separate mixtures containing encapsulated β-carotene, rutin, tiliroside and curcumin and 2% wt Alg were introduced to a jet homogenizer in order to produce the MG particles. Results showed high levels of loading efficiency especially for particles with rutin and tiliroside (>50%), while dependence on the size and possibly the surface charge density of the encapsulated particles was observed [ 45 ]. Calcium-Alg MGs have also been investigated as novel delivery systems of garlic flavor.…”

Section: Polysaccharide Ngs and Mgs Applications In The Food Industrymentioning

confidence: 99%

Current Advances of Polysaccharide-Based Nanogels and Microgels in Food and Biomedical Sciences

Papagiannopoulos

Sotiropoulos²

2022

Polymers

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Polysaccharides are natural polymers with hydrophilic, biocompatible and biodegradable characteristics and have many opportunities in the food and pharmaceutical sectors. This review focuses on the field of nano and microstructures whose internal structure is based on networked polysaccharide chains in 3D i.e., polysaccharide nanogels (NGs) and microgels (MGs). As it is observed the number of articles on NGs and MGs in peer reviewed scientific journals has been increasing over the last two decades. At the same time, the relative contribution of polysaccharides in this field is gaining place. This review focuses on the different applied methods for the fabrication of a variety of polysaccharide-based NGs and MGs and aims to highlight the recent advances on the subject and present their potentials and properties with regards to their integration in aspects of medicinal and food sciences. The presentation of the recent advances in the application of polysaccharide NGs and MGs is divided in materials with potential as emulsion stabilizers and materials with potential as carriers of bioactives. For applications in the medical sector the division is based on the fabrication processes and includes self-assembled, electrostatically complexed/ionically crosslinked and chemically crosslinked NGs and MGs. It is concluded that many advances are expected in the application of these polysaccharide-based materials and in particular as nutrient-loaded emulsion stabilizers, viscosity modifiers and co-assembled structures in combination with proteins.

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Section: Polysaccharide Ngs and Mgs Applications In The Food Industrymentioning

confidence: 99%

Current Advances of Polysaccharide-Based Nanogels and Microgels in Food and Biomedical Sciences

Papagiannopoulos

Sotiropoulos²

2022

Polymers

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“…About 1 to 2 ml of microgel suspension was placed on top of the plate. The applied shear rate ranged from 0.1 to 10 s -1 for each sample [19].…”

Section: Rheology Testmentioning

confidence: 99%

“…The ζ-potentials of then hydrogel particles were measured using Zetasizer Nano-Z by having modification of methods from Pravinata [19]. The samples were placed in folded capillary electrophoresis cells DTS1070 (Malvern, Worchestershire, UK).…”

Section: Zeta Potentialmentioning

confidence: 99%

Rheological Assessments on Alginate and Carrageenan as Nanoparticle Carriers for Topical Oral Cancer Drug

Burhan,

Suffian,

Zakaria

et al. 2023

J.Trop.Life.Science

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Commercially available topical oral drugs in current markets have low efficacy in delivery active load to the infected site due to poor formulation. Delivery of the active ingredients proven to be challenging as compared to skin due the presence of saliva and low shear. The aim of this project to improve formulation and characterised suitable hydrogels which later will be incorporated with nanoparticle drug for oral cancer. The gels are formulated at different pH values (4, 7, 10) and concentrations as such (0.1%, 0.15%, 0.2%, 0.25%, 0.5% and 1.0% for alginate whereas kappa-carrageenan and iota-carrageenan were formulated with 0.25%, 0.5% and 1.0%). The viscosity and zeta potential of the formulated gels are studied using HAAKE™ MARS™ rheometer and Zetasiser Nano-Z respectively. Findings revealed both 1% of kappa-carrageenan and 1% iota-carrageenan of pH 4 and pH 7 are the best candidates for nanoparticle drug delivery as the viscosity and zeta potential for 1% kappa-carrageenan (pH 4), 1% kappa-carrageenan (pH 7), 1% iota-carrageenan (pH 4), and 1% iota-carrageenan (pH 7) amongst the highest as such 70.507±6.190, 61.040±3.199, 59.490±7.799, 67.953±2.034 Pa·s, correspondingly with zeta potential value of -19.4 mV, -20.6 mV, -33.1 mV and -30.4 mV. All hydrogels formulated with different concentration were affected by pH values, by having pH value 4 and 7 appeared to have high viscosity with pseudoplastic behaviour based on the rheological profile, except for alginate due to high density sodium alginate was used in this study.

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Non‐Extractable Polyphenols Should be Systematically Included in Polyphenol Analysis

Báez‐García

Sáyago‐Ayerdi

Pérez‐Jiménez

2023

Recent Advances in Polyphenol Research

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Encapsulation of water-insoluble polyphenols and β-carotene in Ca-alginate microgel particles produced by the Leeds Jet Homogenizer

Abstract: This is a repository copy of Encapsulation of water-insoluble polyphenols and β-carotene in Ca-alginate microgel particles produced by the Leeds Jet Homogenizer.

Cited by 13 publications

References 26 publications

Current Advances of Polysaccharide-Based Nanogels and Microgels in Food and Biomedical Sciences

Current Advances of Polysaccharide-Based Nanogels and Microgels in Food and Biomedical Sciences

Rheological Assessments on Alginate and Carrageenan as Nanoparticle Carriers for Topical Oral Cancer Drug

Non‐Extractable Polyphenols Should be Systematically Included in Polyphenol Analysis

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