Encefalitis por anticuerpos antirreceptor N-metil-D-aspartato asociada a teratoma ovárico: descripción de un caso e implicaciones anestésicas

Rationale:Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an immune-mediated syndrome caused by the production of antibodies against NMDA receptors. As NMDA receptors are important targets of many anesthetic drugs, the perioperative management of patients with anti-NMDA receptor encephalitis is challenging for anesthesiologists.Patient concerns:A 31-year-old woman presented with akinesia and aphasia, which worsened despite steroid therapy.Diagnosis:Anti-NMDA receptor encephalitis associated with ovarian teratoma.Interventions:Laparoscopic ovarian cystectomy was performed under total intravenous anesthesia (TIVA) with peripheral nerve block (PNB).Outcomes:The patient recovered without postoperative complications or any adverse events after surgery.Lessons:Ideal anesthesia for a patient with anti-NMDA receptor encephalitis is still under discussion. We decided to perform TIVA with PNB because the effect of propofol on NMDA receptors is considered less than that of volatile anesthetics; moreover, PNB may reduce the amount of propofol and opioids required for anesthesia. To conclude, TIVA with PNB may be the most appropriate method for anesthesia in a patient with anti-NMDA receptor encephalitis undergoing ovarian cystectomy.

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Encefalitis por anticuerpos antirreceptor N-metil-D-aspartato asociada a teratoma ovárico: descripción de un caso e implicaciones anestésicas

Cited by 2 publications

References 10 publications

Ovarian teratoma-associated Anti-NMDAR encephalitis in women with first-time neuropsychiatric symptoms: A meta-analysis and systematic review of reported cases

Ovarian teratoma-associated Anti-NMDAR encephalitis in women with first-time neuropsychiatric symptoms: A meta-analysis and systematic review of reported cases

Anesthesia for patient with anti-N-methyl-D-aspartate receptor encephalitis

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