Encephalographic Studies in Manicdepressive Psychosis

Objectives Compare MRI scans of patients with late‐onset schizophrenia, late‐life depression and late‐life bipolar disorder to age‐ and gender‐matched controls. MRI head scans of 14 patients in each diagnostic group and 21 patients in the normal control group were compared. Subjects were recruited from inpatient and outpatient services. Measures The CERAD MRI rating algorithm was used to rate degree of atrophy. Results Patients with bipolar and unipolar disorder had greater left sylvian fissure and left and right temporal sulcal enlargement, and more bilateral cortical atrophy than normals. Patients with late‐onset schizophrenia had larger right temporal horns and larger third ventricles. These findings validate the distinctions between late‐life affective disorder and late‐onset schizophrenia and mirror changes reported in younger individuals. They may reflect underlying structural and functional abnormalities found in neuropathologic and functional imaging studies. Copyright © 2000 John Wiley & Sons, Ltd.

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Röntgendiagnostik des Gehirns und Rückenmarks durch Kontrastverfahren

Guttmann¹

1936

Allgemeine Neurologie VII/2

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Encephalographic Studies in Manicdepressive Psychosis

Cited by 5 publications

References 14 publications

Encephalography

Encephalography

MRI findings differentiate between late-onset schizophrenia and late-life mood disorder

Röntgendiagnostik des Gehirns und Rückenmarks durch Kontrastverfahren

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