Encéphalopathie avec mouvements choréiformes induits par la trimétazidine : à propos d’un cas

Sivet, J.; Gastine, B. de la; Mosquet, Brigitte; Lescure, P.; Boutémy, Jonathan; Boisselier, Reynald Le; Coquerel, Antoine

doi:10.1016/j.revmed.2007.12.001

Cited by 10 publications

(8 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A second round of screening was done applying eligibility criteria to study abstracts and/or full texts. We translated one study (14) wherein the abstract was in English, but the entire article was in French using Google Translate. Thus, a total of five studies were included for the final fulltext review.…”

Section: Resultsmentioning

confidence: 99%

“…The most commonly reported extrapyramidal symptoms were akinesia, rigidity, postural disturbances, and gait disorders (10,(12)(13)(14)(15). These features were usually mild and symmetric (13).…”

Section: Discussionmentioning

confidence: 99%

“…Assessment of risk of bias across studies was not done due to the varying study designs used and the wide range of sample size. One article was not in English and was translated in order to be included in the study to increase the sample size (14).…”

Section: Discussionmentioning

confidence: 99%

“…Most of the studies (n = 4) measured outcomes based on clinical observations (10,12,14,15). One prospective study used the following scales to assess motor and non-motor symptoms: Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), tremor score (TS), postural instability and gait difficulty (PIGD) derived from the UPDRS, 39-item Parkinson's Disease Questionnaire (PDQ-39), Lille Apathy Rating Scale, Non-Motor Symptoms Scale, Montgomery-Asberg Depression Rating Scale, Montreal Cognitive Assessment (MoCA), and Parkinson Anxiety Scale (13).…”

Section: Methodsmentioning

confidence: 99%

“…Other rare but reversible side effects include thrombocytopenia, agranulocytosis, and liver dysfunction (11). However, there have been increasing numbers of reports that TMZ can cause chorea and parkinsonian symptoms (10,(12)(13)(14)(15)(16).…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Trimetazidine-Induced Parkinsonism: A Systematic Review

Limjoco

Jamora

2020

Front. Neurol.

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Trimetazidine-Induced Parkinsonism: A Systematic Review

Limjoco

Jamora

2020

Front. Neurol.

View full text Add to dashboard Cite

show abstract

Drug‐induced parkinsonism: A review of 17 years' experience in a regional pharmacovigilance center in France

Bondon‐Guitton¹,

Pérez-Lloret

Bagheri³

et al. 2011

Movement Disorders

131

105

View full text Add to dashboard Cite

Besides antipsychotics, several drugs can induce parkinsonism. We review spontaneous notifications of drug-induced or -worsened parkinsonism to a French regional pharmacovigilance center between 1993 and 2009. During these 17 years, 20,855 adverse drug reactions have been reported, including 155 (0.7%) cases of drug-induced or -worsened parkinsonism. Most of the notifications have involved aged patients (48% between 60 and 79 years) and females (60%). "Seriousness" was found in 43.9% of cases. Worsening of parkinsonism occurred in 28 patients suffering from idiopathic Parkinson's disease. Sixty-nine percent of drug-induced or -worsened parkinsonism cases were observed during the first 3 months after introduction of the "suspect" drug (involving mainly central dopaminergic antagonists). A second peak (20%) was found 12 months after drug introduction (mainly caused by calcium channel blockers). The most frequently reported parkinsonian symptom was rigidity (78.7%). The three cardinal symptoms were found in 37.4% of notifications. Evolution was favorable (after partial or complete withdrawal of suspect drug[s]) in 88.7% of cases. Among the 261 suspect drugs, most involved central dopaminergic antagonists (49%), followed by antidepressants (8%), calcium channel blockers (5%), peripheral dopaminergic antagonists (5%), and H1 antihistamines (5%). Cases with lithium, valproic acid, amiodarone, anticholinesterases, or trimetazidine were also found. Three notifications were the result of pharmacokinetic interactions. We found that drug-induced or -worsened parkinsonism is an often "serious," but reversible, adverse drug reaction. It occurred more frequently between 60 and 79 years. Rigidity was the most frequently reported symptom. Approximately 50% of drug-induced or -worsened parkinsonism cases spontaneously reported were related to drugs other than antipsychotics. Drug-induced or -worsened parkinsonism can also be explained by pharmacokinetic drug interactions.

show abstract

Current awareness: Pharmacoepidemiology and drug safety

2008

Pharmacoepidemiology and Drug

View full text Add to dashboard Cite

In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of pharmacoepidemiology and drug safety. Each bibliography is divided into 20 sections: 1 Reviews; 2 General; 3 Anti‐infective Agents; 4 Cardiovascular System Agents; 5 CNS Depressive Agents; 6 Non‐steroidal Anti‐inflammatory Agents; 7 CNS Agents; 8 Anti‐neoplastic Agents; 9 Haematological Agents; 10 Neuroregulator‐Blocking Agents; 11 Dermatological Agents; 12 Immunosuppressive Agents; 13 Autonomic Agents; 14 Respiratory System Agents; 15 Neuromuscular Agents; 16 Reproductive System Agents; 17 Gastrointestinal System Agents; 18 Anti‐inflammatory Agents ‐ Steroidal; 19 Teratogens/fetal exposure; 20 Others. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted.

show abstract

Encéphalopathie avec mouvements choréiformes induits par la trimétazidine : à propos d’un cas

Cited by 10 publications

References 6 publications

Trimetazidine-Induced Parkinsonism: A Systematic Review

Trimetazidine-Induced Parkinsonism: A Systematic Review

Drug‐induced parkinsonism: A review of 17 years' experience in a regional pharmacovigilance center in France

Current awareness: Pharmacoepidemiology and drug safety

Contact Info

Product

Resources

About