Encoding the future: Successful processing of intentions engages predictive brain networks

Poppenk, Jordan; Moscovitch, Morris; McIntosh, Anthony R.; Ozcelik, Erol; Craik, Fergus I. M.

doi:10.1016/j.neuroimage.2009.08.049

Cited by 63 publications

(60 citation statements)

References 52 publications

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“…Poppenk et al (43) had participants view scenes in the scanner and either generate future intentions or present actions associated with the scenes. Postscan, participants viewed scene cues and recalled whether the cues were seen in the scanner and if so, under what task conditions (i.e., generating an intention or a present action).…”

Section: Discussionmentioning

confidence: 99%

A role for the hippocampus in encoding simulations of future events

Martin

Schacter

Corballis

et al. 2011

Proc. Natl. Acad. Sci. U.S.A.

138

132

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The role of the hippocampus in imagining the future has been of considerable interest. Preferential right hippocampal engagement is observed for imagined future events relative to remembered past events, and patients with hippocampal damage are impaired when imagining detailed future events. However, some patients with hippocampal damage are not impaired at imagining, suggesting that there are conditions in which the hippocampus may not be necessary for episodic simulation. Given the known hippocampal role in memory encoding, the hippocampal activity associated with imagining may reflect the encoding of simulations rather than event construction per se. The present functional (f)MRI study investigated this possibility. Participants imagined future events in response to person, place, and object cues. A postscan cued-recall test probing memory for detail sets classified future events as either successfully encoded or not. A contrast of successfully versus unsuccessfully encoded events revealed anterior and posterior right hippocampal clusters. When imagined events were successfully encoded, both anterior and posterior hippocampus showed common functional connectivity to a network including parahippocampal gyrus, medial parietal and cingulate cortex, and medial prefrontal cortex. However, when encoding was unsuccessful, only the anterior hippocampus, and not the posterior, exhibited this pattern of connectivity. These findings demonstrate that right hippocampal activity observed during future simulation may reflect the encoding of the simulations into memory. This function is not essential for constructing coherent scenarios and may explain why some patients with hippocampal damage are still able to imagine the future.

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Section: Discussionmentioning

confidence: 99%

A role for the hippocampus in encoding simulations of future events

Martin

Schacter

Corballis

et al. 2011

Proc. Natl. Acad. Sci. U.S.A.

138

132

View full text Add to dashboard Cite

show abstract

“…For blocks associated with "action" instructions, participants imagined themselves performing an action in the scene; for blocks associated with "intention" instructions, participants associated a future intention with the scene. Because we wished to relate any novelty and subsequent memory effects to findings reported by other investigators, and these effects are not typically assessed in the context of prospective memory, we did not include any data from the intention encoding condition in the current study [our findings on prospective memory are described by Poppenk et al (2010a)]. Following the presentation of each stimulus, participants pressed a key on an MR-compatible keypad to indicate successful generation of an action or intention.…”

Section: Methodsmentioning

confidence: 99%

Past Experience Modulates the Neural Mechanisms of Episodic Memory Formation

Poppenk¹,

McIntosh²,

Craik³

et al. 2010

J. Neurosci.

Self Cite

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Neuroscientists have observed the "birth" of memories, but have not explored how an organism's past experience with materials interacts with the neural mechanisms of episodic memory formation. Using functional neuroimaging, we searched for such an interaction by examining brain activity during memory encoding that predicted participants' subsequent episodic memory for novel and repeated scenes. Memory for both scene types was predicted by a common posterior network in occipital and parietal cortices. Medial temporal memory predictors were modulated by scene repetition: the right anterior hippocampus and right amygdala predicted memory for novel scenes only, whereas posterior hippocampi predicted memory for repeated scenes only. There was also greater functional connectivity between the temporal pole and anterior versus posterior hippocampus, and this link predicted memory for novel but not repeated scenes. In contrast, there was greater functional connectivity between the precuneus and posterior versus anterior hippocampus, and this link predicted memory for repeated but not novel scenes. Together, these results reveal a functional specialization within the hippocampus for the encoding of novel and previously experienced materials, and suggest that the topography of this specialization might be related to local variations in connectivity. Because episodic memory for repeated scenes was superior, our results also support traditional views of encoding emphasizing the role of prior representations, and illuminate one way in which humans use existing memories to help form new ones. In so doing, our results challenge recent novelty-encoding hypotheses.

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“…In contrast, FPCN A regions are activated when attention is directed towards one's own thoughts and away from perceptual inputs 40,63,64 , for example, during tasks that require metacognitive awareness 63,65,66 , relational reasoning 67 , multi-tasking and complex task sets 43,60,[68][69][70] , stimulus-independent and abstract thinking 34,41,64,[71][72][73] , mentalizing 74 , episodic memory 55,75 , future planning 5 , and prospective memory 76 . Consistent with this, we found that FPCN A was preferentially coupled with the DN, which plays a role in bringing conceptual/associative knowledge to bear on current thought and perception [28][29][30]37,77 .…”

Section: Functional Organization Of the Fpcnmentioning

confidence: 99%

Heterogeneity Within the Frontoparietal Control Network and its Relationship to the Default and Dorsal Attention Networks

Dixon

Vega

Mills

et al. 2017

Preprint

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The frontoparietal control network (FPCN) plays a central role in executive control. It has been predominantly viewed as a unitary domain general system. Here, we examined patterns of FPCN functional connectivity (FC) across multiple conditions of varying cognitive demands, in order to test for FPCN heterogeneity. We identified two distinct subsystems within the FPCN based on hierarchical clustering and machine learning classification analyses of within-FPCN FC patterns. These two FPCN subsystems exhibited distinct patterns of FC the default network (DN) and the dorsal attentional network (DAN). This 2-fold FPCN differentiation was observed across four independent data sets, across 9 different conditions (rest and 8 tasks), as well as in meta-analytic co-activation patterns. The extent of FPCN differentiation varied across conditions, suggesting flexible adaptation to task demands. These findings reveal a flexible and heterogeneous FPCN organization that may in part emerge from separable DN and DAN processing streams.

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Encoding the future: Successful processing of intentions engages predictive brain networks

Cited by 63 publications

References 52 publications

A role for the hippocampus in encoding simulations of future events

A role for the hippocampus in encoding simulations of future events

Past Experience Modulates the Neural Mechanisms of Episodic Memory Formation

Heterogeneity Within the Frontoparietal Control Network and its Relationship to the Default and Dorsal Attention Networks

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