End-Stage Renal Disease and Sudden Cardiac Death

Sakhuja, Rahul; Hiremath, Swapnil; Thakur, Ranjan K.

doi:10.1016/j.ccep.2009.08.006

Cited by 5 publications

(4 citation statements)

References 173 publications

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“…Cardiovascular disease is the most common cause of mortality in the ESKD population. 62 Much of this increased risk is secondary to traditional risk factors including diabetes mellitus, dyslipidemia, and hypertension. Exercise has been shown to improve insulin resistance 63 and lower glucose levels in patients either at risk for or diagnosed with type 2 diabetes mellitus.…”

Section: Discussionmentioning

confidence: 99%

Physical Activity in Patients Treated With Peritoneal Dialysis: A Systematic Review and Meta-analysis

Thangarasa

Imtiaz

Hiremath

et al. 2018

Can J Kidney Health Dis

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Background:Exercise has been shown to be of benefit in the general population and in patients with chronic diseases. Despite a lack of compelling evidence, patients with end-stage kidney disease (ESKD) treated with peritoneal dialysis (PD) are often discouraged from participating in exercise programs that include weight lifting due to concerns about the development of hernias and leaks. The actual effects of physical activity with or without structured exercise programs for patients on PD remain unclear.Objective:To determine the risks and benefits of physical activity in the ESKD population treated with PD.Design:Systematic review and meta-analysis.Setting:Included all studies that met our criteria regardless of country of origin.Patients:Adult patients with ESKD treated with PD.Measurements:Descriptive and quantitative analysis of our primary and secondary outcome variables.Methods:We searched MEDLINE, Embase, CINAHL, and Cochrane Central Register of Controlled Trials for observational and interventional studies examining the effects of physical activity in patients on PD. A systematic review and meta-analysis was conducted of the identified studies. The primary outcomes of interest included patient-centered outcomes of mental health, physical functioning, fatigue, quality of life, and adverse events. Secondary outcomes included nutritional measures, lipid profile, blood pressure changes, maximum heart rate, resting heart rate, maximal oxygen consumption, muscle development, cognitive function, and markers of inflammation.Results:Of 1828 studies identified by the literature search, 12 met the inclusion criteria including 6 interventional and 6 observational studies. There was limited information on the patient important outcomes. However, there is some evidence for improvements in burden of kidney disease, physical function, and some mental health measures with physical activity.Limitations:Lack of well-designed randomized controlled trials impaired our ability to determine the benefits and risks of increasing physical activity.Conclusions:There is limited evidence of benefit with increased levels of physical activity in PD patients. Further research is needed to define the exercise program that is likely to be of most benefit to patients treated with PD.

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Section: Discussionmentioning

confidence: 99%

Physical Activity in Patients Treated With Peritoneal Dialysis: A Systematic Review and Meta-analysis

Thangarasa

Imtiaz

Hiremath

et al. 2018

Can J Kidney Health Dis

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“…Autonomic neuropathy and impairment of left ventricular functions have been frequently encountered in chronic renal failure and depend on the disease duration (Karayaylali et al, 2003). (Dubrava et al, 2003;Sakhuja et al, 2009). SAECG parameters are abnormal in a significant proportion of patients with chronic renal failure (Girgis et al, 1999).…”

Section: End-stage Renal Failure and Hemodialysismentioning

confidence: 99%

Late Ventricular Potentials in Cardiac and Extracardiac Diseases

Mozoş¹,

Şerban²,

Mihăescu³

2012

Cardiac Arrhythmias - New Considerations

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“…Autonomic neuropathy and impairment of left ventricular functions have been frequently encountered in chronic renal failure and depend on the disease duration (Karayaylali et al, 2003). SCD risk due to ventricular arrhythmias is high in ESRD patients on hemodialysis (HD) (Dubrava et al, 2003;Sakhuja et al, 2009). SAECG parameters are abnormal in a significant proportion of patients with chronic renal failure (Girgis et al, 1999).…”

Section: End-stage Renal Failure and Hemodialysismentioning

confidence: 99%

Cardiac Arrhythmias - New Considerations

Breijo-Marquez¹

2012

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End-Stage Renal Disease and Sudden Cardiac Death

Cited by 5 publications

References 173 publications

Physical Activity in Patients Treated With Peritoneal Dialysis: A Systematic Review and Meta-analysis

Physical Activity in Patients Treated With Peritoneal Dialysis: A Systematic Review and Meta-analysis

Late Ventricular Potentials in Cardiac and Extracardiac Diseases

Cardiac Arrhythmias - New Considerations

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