End‐tidal CO2 and transcutaneous CO2: Are we ready to replace arterial CO2 in awake children?

Dicembrino, Manuela; Barbieri, Irene Alejandra; Pereyra, Carla; Leske, Vivian

doi:10.1002/ppul.25217

Cited by 8 publications

(2 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, recent evidence of comparable cerebrovascular reactivity to carbon dioxide in children versus adults, albeit with a slower rate of change in children ( 37 , 38 ) indicates that sensitivity to carbon dioxide does not explain the different trajectories in response to exercise. Moreover, the idea that age-related differences in CBv are driven by carbon dioxide is further challenged by the use of

as a surrogate for

( 39 – 41 ). At rest,

provides a good index of

( 42 ).…”

Section: Discussionmentioning

confidence: 99%

The influence of maturation and sex on intracranial blood velocities during exercise in children

Douglas,

Talbot,

Perkins

et al. 2024

Journal of Applied Physiology

View full text Add to dashboard Cite

Cerebral blood velocity (CBv) increases in response to moderate exercise in humans, but the magnitude of change is smaller in children compared to post-pubertal adolescents and adults. Whether sex differences exist in the anterior or posterior CBv response to exercise across pubertal development remains to be determined. We assessed middle cerebral artery (MCAv) and posterior cerebral artery (PCAv) blood velocity via transcranial Doppler in 38 pre-pubertal (18 male) and 48 post-pubertal (23 male) with cerebrovascular and cardiorespiratory measures compared at baseline and ventilatory threshold. At baseline, MCAv was higher in both sexes pre- vs. post-puberty. Females demonstrated a greater MCAv ( P<0.001) than their male counterparts (pre-pubertal females; 78 ± 11cm.s-1 vs. pre-pubertal males; 72 ± 8cm.s-1, and post- pubertal females; 68 ± 10cm.s-1 vs. post- pubertal males; 62 ± 7cm.s-1). During exercise, MCAv remained higher in post-pubertal females vs. males (81 ± 15 cm.s-1 vs. 73 ± 11 cm.s-1), but there were no differences pre-puberty. The relative increase in PCAv was greater in post- vs pre-pubertal females (51 ± 9cm.s-1 vs. 45 ± 11cm.s-1; P=0.032), but was similar in males and females. Our findings suggest biological sex alters anterior cerebral blood velocities at rest in both pre- and post-pubertal youth, but the response to submaximal exercise is only influenced by sex post-puberty.

show abstract

as a surrogate for

( 39 – 41 ). At rest,

provides a good index of

( 42 ).…”

Section: Discussionmentioning

confidence: 99%

The influence of maturation and sex on intracranial blood velocities during exercise in children

Douglas,

Talbot,

Perkins

et al. 2024

Journal of Applied Physiology

View full text Add to dashboard Cite

show abstract

“…Arterial carbon dioxide pressure (PaCO 2 ) is one of the most critical indicators of a patient’s respiratory function. The gold standard for measuring PaCO 2 in clinical practice is arterial blood gas analysis (ABGA) [ 1 ]. The patient’s acid–base balance and electrolyte state can be determined using ABGA.…”

Section: Introductionmentioning

confidence: 99%

Noninvasive carbon dioxide monitoring in pediatric patients undergoing laparoscopic surgery: transcutaneous vs. end-tidal techniques

et al. 2023

View full text Add to dashboard Cite

Purpose The present study aimed to investigate the correlation between transcutaneous carbon dioxide partial pressure (PtcCO2) and arterial carbon dioxide pressure (PaCO2) and the accuracy of PtcCO2 in predicting PaCO2 during laparoscopic surgery in pediatric patients. Methods Children aged 2–8 years with American Society of Anesthesiologists (ASA) class I or II who underwent laparoscopic surgery under general anesthesia were selected. After anesthesia induction and tracheal intubation, PtcCO2 was monitored, and radial arterial catheterization was performed for continuous pressure measurement. PaCO2, PtcCO2, and end-tidal carbon dioxide partial pressure (PetCO2) were measured before pneumoperitoneum, and 30, 60, and 90 min after pneumoperitoneum, respectively. The correlation and agreement between PtcCO2 and PaCO2, PetCO2, and PaCO2 were evaluated. Results A total of 32 patients were eventually enrolled in this study, resulting in 128 datasets. The linear regression equations were: PtcCO2 = 7.89 + 0.82 × PaCO2 (r2 = 0.70, P < 0.01); PetCO2 = 9.87 + 0.64 × PaCO2 (r2 = 0.69, P < 0.01). The 95% limits of agreement (LOA) of PtcCO2 – PaCO2 average was 0.66 ± 4.92 mmHg, and the 95% LOA of PetCO2 – PaCO2 average was –4.4 ± 4.86 mmHg. A difference of ≤ 5 mmHg was noted between PtcCO2 and PaCO2 in 122/128 samples and between PetCO2 and PaCO2 in 81/128 samples (P < 0.01). Conclusion In pediatric laparoscopic surgery, a close correlation was established between PtcCO2 and PaCO2. Compared to PetCO2, PtcCO2 can estimate PaCO2 accurately and could be used as an auxiliary monitoring indicator to optimize anesthesia management for laparoscopic surgery in children; however, it is not a substitute for PetCO2. Registration number of Chinese Clinical Trial Registry ChiCTR2100043636.

show abstract

Resuscitation

Welsby¹

2023

The Great Ormond Street Hospital Manual of Children and Young People's Nursing Practices

View full text Add to dashboard Cite

End‐tidal CO₂ and transcutaneous CO₂: Are we ready to replace arterial CO₂ in awake children?

Cited by 8 publications

References 37 publications

The influence of maturation and sex on intracranial blood velocities during exercise in children

The influence of maturation and sex on intracranial blood velocities during exercise in children

Noninvasive carbon dioxide monitoring in pediatric patients undergoing laparoscopic surgery: transcutaneous vs. end-tidal techniques

Resuscitation

Contact Info

Product

Resources

About