Endobronchial metastasis: An epidemiologic and clinicopathologic study of 174 consecutive cases

Abstract

Endobronchial metastases from extrapulmonary tumors account for about 4% of all bronchoscopic biopsies performed for suspected malignancy and in 5% of the cases the metastasis is the first manifestation of the neoplasm.

Unusual Patterns of Thoracic Metastasis of Urinary Bladder Carcinoma

“…[2829] Summation of the available series, some of them relatively large, would yield under a dozen cases of endobronchial disease in UBC, and such cases are entirely absent from a few of these reports. [303132333435] Breast, colorectal, and renal cell are the most common primary sites associated with endobronchial spread. [34] This tends to be a late manifestation of the respective primary tumor and is almost always a metachronous occurrence.…”

“…[34] This tends to be a late manifestation of the respective primary tumor and is almost always a metachronous occurrence. [35] At the time of presentation with endobronchial metastasis, involvement of other distant sites is usually detectable as well. The typical symptoms of endobronchial malignancy are cough, dyspnea, hemoptysis, and focal wheezing.…”

Endobronchial metastases of colorectal cancer

“…Twenty six percent of these lesions are due to colorectal cancer (2). One single case of anal origin has been reported (3).…”

“…Lung metastases from colorectal cancer arise in the pulmonary parenchyma; however metastases on the tracheobronchial wall are anecdotal (2).…”

Spontaneous expectoration of pulmonary metastases in a child with osteogenic sarcoma

“…To the Editor: Pulmonary metastases from solid tumors can be parenchymal (peripheral) or endobronchial (central) . Endobronchial metastases are rare events, most frequently reported with breast, colorectal, kidney, stomach, and prostate primaries . Occasionally, endobronchial metastases present with spontaneous expectoration of the metastatic tissue .…”