Endobronchial Metastasis from Renal Cell Carcinoma as a Reason for Recurrent Pulmonary Infections

Chrysikos, Serafeim; Karampitsakos, Theodoros; Tzouvelekis, Argyrios; Dimakou, Katerina

doi:10.5603/arm.2018.0039

Cited by 8 publications

(8 citation statements)

References 12 publications

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“…The most common symptoms mentioned are cough and hemoptysis followed by dyspnea and wheezing in patients with EBM. [ 10 11 12 13 14 15 16 ] In our series, cough was the most frequent symptom followed by chest pain and dyspnea. This indicates that if there is any one of these symptoms in a patient with extrapulmonary malignancy, especially breast, colon or renal tumors, bronchoscopic examination is must to exclude EBM.…”

Section: Discussionmentioning

confidence: 53%

“…According to the literature, EBM is observed in various types of malignancies, including colorectal, breast, kidney, stomach, ovarian, thyroid, uterine, testicular, nasopharynx, prostate, adrenal carcinomas, sarcomas, histiocytoma, and plasmacytomas. [ 10 11 12 13 14 15 16 ] The most common EBM is from carcinomas of the colorectal region followed by the breast and kidney. [ 13 14 15 ] This was very well correlated with our study as carcinoma breast and colon were the most common.…”

Section: Discussionmentioning

confidence: 99%

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Endobronchial metastasis from extrathoracic malignancies: A clinicopathological study of 11 cases

et al. 2019

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Section: Discussionmentioning

confidence: 53%

Section: Discussionmentioning

confidence: 99%

Endobronchial metastasis from extrathoracic malignancies: A clinicopathological study of 11 cases

et al. 2019

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“…When surgery is not possible, chemotherapy and external radiotherapy may be considered, especially in localized occluding lesions. However, they are limited of efficacy in RCC metastases, as they do not respond well to such modalities [ 21 , 22 ].…”

Section: Discussionmentioning

confidence: 99%

“…Many palliative modalities can be also contemplated in the late stages of the tumor progression. These modalities include endobronchial therapies such as cryotherapy, laser therapy, brachytherapy, diathermic snares, intratumoral ethanol injections, argon plasma coagulation (APC), and stents [ 4 , 22 ].…”

Section: Discussionmentioning

confidence: 99%

Endobronchial metastasis secondary to occulting renal cell carcinoma: literature review and a rare case report

Rahman

Rajab

et al. 2023

BMC Pulm Med

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Background Endobronchial Metastasis from extrathoracic tumors is a rare neoplasm that accounts for approximately 1.1% of total endobronchial malignancies. The most common primary tumors associated with EBM are from the colorectal, breast, and kidney regions. Although it represents a late manifestation in the context of tumor progression, it can rarely antedate the diagnosis of the primary tumor. Case presentation A 67-years-old male was referred from another city hospital to our thoracic surgery department due to a 4-months history of hemoptysis and productive cough. A chest X-ray and computed tomography scan showed a soft-tissue mass within the left main bronchus and atelectasis of the anterior segment of the left upper lobe. Furthermore, a flexible bronchoscopy revealed a hypervascular lesion occluding completely the left upper lobe bronchus. The patient underwent lobectomy and pathological examination suggested endobronchial metastasis from clear cell renal cell carcinoma. A second computed tomography scan of the abdomen and pelvis showed a well-defined mass arising from the lateral aspect of the right kidney; therefore, the patient underwent right radical nephrectomy three weeks later and pathology confirmed the diagnosis of clear renal cell carcinoma with endobronchial metastasis. Conclusion Despite its rarity, physicians should consider the possibility of endobronchial metastases in the setting of endobronchial lesions. Proper diagnostic approaches should also be considered to rule out the potential of asymptomatic extrathoracic neoplasms. In this manuscript, we aimed to report a rare case -the first from Syria to our knowledge- of an endobronchial metastasis that preceded the diagnosis of renal cell carcinoma. Importantly, we reviewed the existing literature and discussed the diagnostic and treatment approaches.

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“…Those with advanced esophageal cancer, complicated by an obstruction, have an increased the risk of aspiration pneumonia. Endobronchial lung tumors are associated with chronic inflammation and recurrent post-obstructive infections [16]. Intra-abdominal tumors obstructing the genitourinary or hepato-biliary tracts may result in severe urinary tract infections or cholangitis [17,18].…”

Section: Management Of Febrile Neutropenia During Covid-19mentioning

confidence: 99%

Emerging challenges in the evaluation of fever in cancer patients at risk of febrile neutropenia in the era of COVID-19: a MASCC position paper

Cooksley¹,

Font

Scotté

et al. 2020

Support Care Cancer

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Patients with cancer are at higher risk of more severe COVID-19 infection and have more associated complications. The position paper describes the management of cancer patients, especially those receiving anticancer treatment, during the COVID-19 pandemic. Dyspnea is a common emergency presentation in patients with cancer with a wide range of differential diagnoses, including pulmonary embolism, pleural disease, lymphangitis, and infection, of which SARS-CoV-2 is now a pathogen to be considered. Screening interviews to determine whether patients may be infected with COVID-19 are imperative to prevent the spread of infection, especially within healthcare facilities. Cancer patients testing positive with no or minimal symptoms may be monitored from home. Telemedicine is an option to aid in following patients without potential exposure. Management of complications of systemic anticancer treatment, such as febrile neutropenia (FN), is of particular importance during the COVID-19 pandemic where clinicians aim to minimize patients' risk of infection and need for hospital visits. Outpatient management of patients with low-risk FN is a safe and effective strategy. Although the MASCC score has not been validated in patients with suspected or confirmed SARS-CoV-2, it has nevertheless performed well in patients with a range of infective illnesses and, accordingly, it is reasonable to expect efficacy in the clinical setting of COVID-19. Risk stratification of patients presenting with FN is a vital tenet of the evolving sepsis and pandemic strategy, necessitating access to locally formulated services based on MASCC and other national and international guidelines. Innovative oncology services will need to utilize telemedicine, hospital at home, and ambulatory care services approaches not only to limit the number of hospital visits but also to anticipate the complications of the anticancer treatments.

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Endobronchial Metastasis from Renal Cell Carcinoma as a Reason for Recurrent Pulmonary Infections

Cited by 8 publications

References 12 publications

Endobronchial metastasis from extrathoracic malignancies: A clinicopathological study of 11 cases

Endobronchial metastasis from extrathoracic malignancies: A clinicopathological study of 11 cases

Endobronchial metastasis secondary to occulting renal cell carcinoma: literature review and a rare case report

Emerging challenges in the evaluation of fever in cancer patients at risk of febrile neutropenia in the era of COVID-19: a MASCC position paper

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