Endobronchial recurrence of non-Hodgkin’s lymphoma mimicking foreign body aspiration

Abstract

Abstract:A 2-year-old patient with a history of non-Hodgkin's lymphoma (NHL) was presented to our hospital with the complaint of shortness of breath and wheezing. Posteroanterior chest radiograph revealed hyperlucency and hyperexpansion of the right hemithorax. We performed computed tomography (CT) because of a suspicion of foreign body aspiration. CT revealed right main bronchus occlusion by a hypodense lesion. Bronchoscopy revealed a mass lesion in the right main bronchus which was histopathologically diagnosed as NHL. Only a few cases of endobronchial recurrence of lymphoma have been reported in the current literature, but there is no reported case in a pediatric patient.

Endobronchial primary large B-cell Non-Hodgkin lymphoma in HIV-infected patient in the Highly Active Antiretroviral Therapy era: Description of a case report

“…Tracheobronchial involvement, either primary or secondary, remains a rare event among HIV-patients with NHL and two different clinical and bronchoscopic patterns can be observed [1] , [2] , [3] , [4] , [5] , [6] , [7] , [8] .…”

“…In patients with systemic lymphoma, multiple variable-sized nodules along the tracheobronchial tree can be observed at FOB. This bronchoscopic picture corresponding to Type 1, is related to varying degrees of submucosal lymphatic involvement from lymphatic network draining lymph from the pulmonary parenchyma into mediastinum [2] , [3] , [4] , [5] , [6] , [7] , [8] , [9] .…”

“…Conversely solitary polypoid tumor due to direct spread of lymphoma from adjacent lymph nodes or arising de novo from bronchus-associated lymphoid tissue has been associated with airway obstruction (cough, wheezing or hemoptysis) [4] , [5] , [6] , [7] , [8] .…”