Endobronchial tuberculosis in HIV-infected patients

Calpe, J.L.; Chiner, E.; Larramendi, Carlos H.

doi:10.1097/00002030-199510000-00007

Cited by 30 publications

(9 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of these 62 patients, 43 patients continued to have endobronchial tuberculosis by the end of treatment; and despite appropriate treatment with anti-tuberculous therapy approximately 50% (22/43 patients) of the patients developed bronchostenosis. This pattern is consistent with other previous studies (30)(31)(32). Among 19 cases with granular, ulcerative, and nonspecific bronchitic endobronchial tuberculosis that did not show luminal narrowing of the bronchus at diagnosis, 17 cases healed without bronchostenosis, while 2 cases of granular type still developed bronchial stenosis after treatment.…”

Section: Treatmentsupporting

confidence: 92%

Tracheobronchial tuberculosis

Pathak¹,

Shepherd²,

Shojaee³

2016

J. Thorac. Dis.

View full text Add to dashboard Cite

Tracheobronchial tuberculosis (TBTB) is reported in approximately 10% to 39% of the patients with pulmonary tuberculosis. It is defined as the tubercle infection of the trachea and or bronchi. Due to its non-specific presentation, insidious onset and normal chest radiography in about 10-20% of the patients, the diagnosis is delayed. Bronchoscopy is the most definite method of diagnosis which provides adequate specimens for microbiological and histopathological diagnosis. Tracheobronchial stenosis is one of the most common long term complications of TBTB resulting in significant morbidity. It is estimated that 90% of patients with TBTB have some degree of tracheal and or bronchial stenosis. In this review article, we will discuss the pathogenesis, symptoms, imaging, bronchoscopic findings, and treatment of TBTB and management of tracheobronchial stenosis.

show abstract

Section: Treatmentsupporting

confidence: 92%

Tracheobronchial tuberculosis

Pathak¹,

Shepherd²,

Shojaee³

2016

J. Thorac. Dis.

View full text Add to dashboard Cite

show abstract

“…Endobronchial tuberculosis (EBTB) is a special form of pulmonary tuberculosis. About 10% to 40% of patients with active pulmonary tuberculosis had EBTB as reported in previous studies [5,6]. The diagnosis of typical pulmonary tuberculosis is easily confirmed by bacteriological means and radiological findings.…”

Section: Introductionsupporting

confidence: 53%

Investigation of endobronchial tuberculosis diagnoses in 22 cases

Xue

Wang

2010

Eur J Med Res

View full text Add to dashboard Cite

BackgroundEndobronchial tuberculosis (EBTB) is a special form of pulmonary tuberculosis. In spite of much progress in the diagnosis of this disease in past years, delayed or mistaken diagnosis is still commonly seen.ObjectiveThe aim of this study is to try to find out some useful clues for the diagnosis of EBTB, especially the early diagnosis.MethodsThe medical records of patients with EBTB were analyzed retrospectively. Results: The male-to-female ratio was 1:2.2 out of 22 patients. Patients aged below 60-years-old constituted 72.7% of the cases. 22.7% of these patients were smokers. The male-to-female ratio of smokers was 4:1. 68.2% of these patients tested all showed negative result for the HIV test. The frequent complaints were cough, sputum, shortness of breath and fever, and antibiotic treatments were usually inefficacious. Multiple lobes lesion, exudative shadow and atelectasis were the frequent radiological findings. Acid-fast bacilli staining for sputum smear was positive in only 13.6% of these patients. Tuberculin skin test was positive in 59.1% of these patients. Granular lesion was the most common bronchoscopic appearance in these patients. Histological changes showed distinctive tuberculose lesion in 72.2% of 18 patients undergoing bronchoscopic biopsy.ConclusionThe diagnosis of EBTB is easily delayed or mistaken because of nonspecific clinical manifestations and the low incidence of positive acid-fast bacilli staining. A high index of awareness of this disease is required for diagnosis. Bronchoscopy should be performed as soon as possible in suspected patients, especially when patients present positive tuberculin skin test or no response to antibiotic treatments.

show abstract

“…Previous studies have reported that 10-40% of patients with active pulmonary tuberculosis have EBTB. (5,6) EBTB can mimic a variety of pulmonary diseases such as bronchogenic carcinoma, pneumonia, and bronchial asthma. The diagnosis of typical pulmonary tuberculosis is easily confirmed by bacteriological means and on the basis of radiological findings.…”

Section: Introductionmentioning

confidence: 99%

Bronchoscopic diagnostic procedures and microbiological examinations in proving endobronchial tuberculosis

Şimşek¹,

Yapıcı²,

Babalık³

et al. 2016

J. bras. pneumol.

View full text Add to dashboard Cite

Objective: To determine the proportional distribution of endobronchial tuberculosis (EBTB) subtypes and to evaluate the types of bronchoscopic diagnostic procedures that can prove granulomatous inflammation. Methods: This was a retrospective study of 18 HIV-negative patients with biopsy-proven EBTB treated between 2010 and 2014. Results: The most common EBTB subtypes, as classified by the bronchoscopic features, were tumorous and granular (in 22.2% for both). Sputum smear microscopy was performed in 11 patients and was positive for AFB in 4 (36.3%). Sputum culture was also performed in 11 patients and was positive for Mycobacterium tuberculosis in 10 (90.9%). Smear microscopy of BAL fluid (BALF) was performed in 16 patients and was positive for AFB in 10 (62.5%). Culture of BALF was also performed in 16 patients and was positive for M. tuberculosis in 15 (93.7%). Culture of BALF was positive for M. tuberculosis in 93.7% of the 16 patients tested. Among the 18 patients with EBTB, granulomatous inflammation was proven by the following bronchoscopic diagnostic procedures: bronchial mucosal biopsy, in 8 (44.4%); bronchial brushing, in 7 (38.8%); fine-needle aspiration biopsy, in 2 (11.1%); and BAL, in 2 (11.1%). Bronchial anthracofibrosis was observed in 5 (27.7%) of the 18 cases evaluated. Conclusions: In our sample of EBTB patients, the most common subtypes were the tumorous and granular subtypes. We recommend that sputum samples and BALF samples be evaluated by smear microscopy for AFB and by culture for M. tuberculosis, which could increase the rates of early diagnosis of EBTB. We also recommend that bronchial brushing be employed together with other bronchoscopic diagnostic procedures in patients suspected of having EBTB.

show abstract

Endobronchial tuberculosis in HIV-infected patients

Cited by 30 publications

References 0 publications

Tracheobronchial tuberculosis

Tracheobronchial tuberculosis

Investigation of endobronchial tuberculosis diagnoses in 22 cases

Bronchoscopic diagnostic procedures and microbiological examinations in proving endobronchial tuberculosis

Contact Info

Product

Resources

About