Endobronchial tumor debulking with a flexible cryoprobe for immediate treatment of malignant stenosis

Schümann, Christian; Hetzel, M; Babiak, Anna; Hetzel, Jürgen; Merk, T; Wibmer, Thomas; Lepper, Philipp M.; Krüger, Stefan

doi:10.1016/j.jtcvs.2009.06.023

Cited by 110 publications

(77 citation statements)

References 12 publications

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“…In recent years, cryoprobes have been established for airway recanalisation and for sampling endobronchial lesions, particularly in patients with lung cancer [14][15][16]. Due to the simplicity of handling and the larger biopsy sizes, first reports about the use of cryoprobes for transbronchial biopsies have been published [17,18].…”

Section: Introductionmentioning

confidence: 99%

Endobronchial ultrasound-guided cryobiopsies in peripheral pulmonary lesions: a feasibility study

et al. 2013

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Peripheral lung lesions are sometimes difficult to reach even with endobronchial ultrasound (EBUS) and insufficient material is often obtained by transbronchial forceps biopsy. Cryoprobes can be used for performing tissue biopsies. We evaluated the safety and feasibility of the cryoprobe in combination with EBUS for the diagnosis of peripheral lung lesion.Patients with peripheral lung lesions of up to 4 cm were enrolled. After identifying the lung lesion by radial EBUS, forceps biopsies and cryobiopsies were performed in a randomised order. We evaluated safety and feasibility, and compared diagnostic yield and sample size. 39 patients were randomised and the peripheral lung lesion was reached in 31. The overall diagnostic yield was 60.5% and, in the lesions reached by EBUS, it was 74.2%. In 19 cases, the diagnosis was made with forceps as well as cryobiopsy and, in four cases, only with cryobiopsy. Cryobiopsies were significantly larger than forceps biopsies (11.17 mm 2 versus 4.69 mm 2 , p,0.001). We observed one case of moderate bleeding. Transbronchial cryobiopsy with EBUS guidance is safe and useful to obtain histological samples. Larger tissue samples can be obtained by cryoprobe. @ERSpublications Transbronchial cryobiopsy with EBUS-guidance is safe and useful to obtain samples from peripheral lesions

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Section: Introductionmentioning

confidence: 99%

Endobronchial ultrasound-guided cryobiopsies in peripheral pulmonary lesions: a feasibility study

et al. 2013

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“…In this way, it results in a very effective rapid tumor de-bulking. Through the rapid de-bulking, the airway lumen can be recanalized [1][2][3].…”

Section: Discussionmentioning

confidence: 99%

Cryo-Recanalization of Huge Endobronchial Pulmonary Adenocarcinoma

Rf¹,

Kimmich²,

Wohlleber³

et al. 2017

Oncology and cancer case reports

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A 70-years-old strong smoker (50 pack years) was referred to our center due to increasing dyspnea, coughing and hemoptysis. The patient was in reduced general clinical conditions. The contrast-enhanced tomography revealed huge tumor mass of the right bronchial system (Figure 1). The staging procedure showed multiple osseous, hepatic and lymphatical metastasis. There were no surgical options; a systemic palliative therapy was to be initiated after the histological and immunhistological examination. AbstractWe were able to recanalize the major lumen of the right main bronchial branch, which was completely blocked because of huge tumor mass from the right upper lobe. With the cryo-therapy, we could freeze and remove the major portion of this huge tumor mass.

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“…Технически эндоскопическую криотерапию до середины 90-х годов осуществляли толь-ко посредством ригидной бронхоскопии [12,13]. В после-дующем с совершенствованием оборудования стало воз-можно применять криохирургию и при гибкой фибро-бронхоскопии [14,15]. Несмотря на то что метод криоте-рапии известен очень давно, долгое время он не имел широкого распространения при эндоскопическом лече-нии опухолей дыхательных путей [16].…”

Section: история криохирургииunclassified

New Technologies for C Ryosurgery in Endoscopic Treatment of Lung and Bronchial Tumors

Соколов¹,

Соколов²,

Telegina³

et al. 2017

Med. sov.

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The article presents the history of the development of the cryotherapy method from antiquity to the present day, materials of clinical use of cryosurgery for endoscopic diagnosis and treatment of lung and bronchial tumors at the present stage, features of the advanced equipment for cryosurgery. The article also describes the first clinical experience in using cryorecanalization in obstructing tumors of the tracheobronchial tree in Russia using an advanced cryosurgical device. Three clinical examples of cryorecanalization are provided. The preliminary results of the clinical studies show that cryorecanalization using the advanced medical equipment and a new cryoprobe model is an effective method for recanalization to restore airway patency, which can be used in combination with electrodestruction, argon-plasma and laser coagulation, as compared with older cryosurgery devices.

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Endobronchial tumor debulking with a flexible cryoprobe for immediate treatment of malignant stenosis

Abstract: Cryorecanalization with the flexible cryoprobe for treatment of symptomatic endobronchial tumor stenosis is a safe technique with a high success rate and immediate treatment effect.

Cited by 110 publications

References 12 publications

Endobronchial ultrasound-guided cryobiopsies in peripheral pulmonary lesions: a feasibility study

Endobronchial ultrasound-guided cryobiopsies in peripheral pulmonary lesions: a feasibility study

Cryo-Recanalization of Huge Endobronchial Pulmonary Adenocarcinoma

New Technologies for C Ryosurgery in Endoscopic Treatment of Lung and Bronchial Tumors

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