Endobronchial ultrasound: what is it and when should it be used?

Medford, Andrew R L

doi:10.7861/clinmedicine.10-5-458

Cited by 6 publications

(4 citation statements)

References 35 publications

(26 reference statements)

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“…Major vessel puncture is less likely because of real-time sampling. Infectious complications have rarely been reported, and bacteraemia is usually asymptomatic and clinically insignificant (19).…”

Section: Resultsmentioning

confidence: 99%

Invasive staging of the mediastinum

Wever

Coolen

Verschakelen

2013

Journal of the Belgian Society of Radiology

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Section: Resultsmentioning

confidence: 99%

Invasive staging of the mediastinum

Wever

Coolen

Verschakelen

2013

Journal of the Belgian Society of Radiology

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“…Current clinically available haemodynamic measurements are mainly dependent on optical methods (such as photoplethysmography and laser Doppler flowmetry), sphygmomanometry and ultrasound imaging. Ultrasonic and optical techniques have been combined with bronchoscopy, endoscopy or colonoscopy to monitor the haemodynamics of difficult-to-reach mucosa-lined organs (for example, the stomach, bowels and lungs) 43 , 44 . Endoscopic Doppler optical coherence tomography acquires high-spatial-resolution velocity-variance images of GI mucosal and submucosal blood flow.…”

Section: Diagnostic Attributes Of Surface Mucosamentioning

confidence: 99%

Mucosa-interfacing electronics

et al. 2022

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The surface mucosa that lines many of our organs houses myriad biometric signals and, therefore, has great potential as a sensor–tissue interface for high-fidelity and long-term biosensing. However, progress is still nascent for mucosa-interfacing electronics owing to challenges with establishing robust sensor–tissue interfaces; device localization, retention and removal; and power and data transfer. This is in sharp contrast to the rapidly advancing field of skin-interfacing electronics, which are replacing traditional hospital visits with minimally invasive, real-time, continuous and untethered biosensing. This Review aims to bridge the gap between skin-interfacing electronics and mucosa-interfacing electronics systems through a comparison of the properties and functions of the skin and internal mucosal surfaces. The major physiological signals accessible through mucosa-lined organs are surveyed and design considerations for the next generation of mucosa-interfacing electronics are outlined based on state-of-the-art developments in bio-integrated electronics. With this Review, we aim to inspire hardware solutions that can serve as a foundation for developing personalized biosensing from the mucosa, a relatively uncharted field with great scientific and clinical potential.

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“…It is also able to access the hilar and interlobar lymph nodes, which are inaccessible by mediastinoscopy (6). The excellent diagnostic performance of EBUS-TBNA in the mediastinal staging of non-small-cell lung cancer (NSCLC), based on a sensitivity of 88-93% and a negative predictive value of 76-85%, has been reported in several studies (5,(7)(8)(9)(10)(11).…”

Section: Introductionmentioning

confidence: 99%

“…Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive intervention that makes it possible to perform the cytopathological evaluation of mediastinal lymphadenopathy (5). Additionally, it provides access to lung parenchymal lesions in the adjoining bronchus without endobronchial lesions.…”

Section: Introductionmentioning

confidence: 99%

The Utility of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in Patients with Small-cell Lung Cancer

Kang

Jeong

et al. 2016

Intern. Med.

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Objective Most small-cell lung cancers (SCLCs) are located within the central aspect of the chest and manifest as a mediastinal or hilar lymphadenopathy. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) makes it possible to perform mediastinal and hilar nodal examinations. The purpose of this study was to evaluate the performance of EBUS-TBNA in the diagnosis of SCLC. Methods The diagnostic performances of EBUS-TBNA and/or transesophageal bronchoscopic ultrasoundguided fine-needle aspiration (EUS-FNA-B/E) were calculated using the standard definitions. Patients The study consisted of a retrospective review of the medical records for all patients with histologically proven SCLC who previously underwent EBUS-TBNA and/or EUS-FNA-B/E from May 2009 to September 2014. Results The analysis was based on 161 patients and 299 aspirated specimens. The patient group included 144 males (89%); the median age was 66 years. EBUS-TBNA and/or EUS-FNA-B/E were performed in 239 mediastinal nodes, 39 hilar/interlobar nodes, and 21 lung parenchymal lesions. The median short diameter of the biopsied lesions was 17 mm. The overall sensitivity, specificity, negative predictive value, positive predictive value, and accuracy of EBUS-TBNA and/or EUS-FNA-B/E on a per-person basis were 97.4%, 100%, 60%, 100%, and 97.5%, respectively. The corresponding values on a per-lesion basis were 91.8%, 100%, 73.0%, 100%, and 93.3%, respectively. There were no serious complications related to EBUS-TBNA. Conclusion In our series of patients with SCLC, EBUS-TBNA had an excellent diagnostic yield in the evaluation of mediastinal, hilar and lung parenchymal lesions. Thus, EBUS-TBNA could be a useful and safe diagnostic method with which to evaluate patients with SCLC.

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Endobronchial ultrasound: what is it and when should it be used?

Cited by 6 publications

References 35 publications

Invasive staging of the mediastinum

Invasive staging of the mediastinum

Mucosa-interfacing electronics

The Utility of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration in Patients with Small-cell Lung Cancer

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