Endobronchial Valves for Treatment of Hemoptysis

Endobronchial Valve Placement as Salvage Therapy in the Management of Hemoptysis

“…3,4 They have also been used in the management of hemoptysis in the setting of malignancy. 5 Furthermore, they have been effective in the management of life-threatening hemoptysis. 3 In our case, there was no identifiable etiology of the patient's hemoptysis, but EBV placement was still found to be effective.…”

“…Spiration valves have been used in the management of hemoptysis secondary to malignant and infectious etiologies. 4,5 Zephyr valves have been used in the management of hemoptysis secondary to infectious etiologies. 3 Placement of either valve has appeared safe thus far, without significant adverse effects.…”

“…There are 2 commercially available EBV in the United States, Zephyr valves (PulmonX Inc., Redwood City, CA) and Spiration valves (Olympus Respiratory America, Redmond, WA), both of which have been used in the management of hemoptysis. Spiration valves have been used in the management of hemoptysis secondary to malignant and infectious etiologies 4,5 . Zephyr valves have been used in the management of hemoptysis secondary to infectious etiologies 3 .…”

“…There have been 2 reports of EBV used in the treatment of hemoptysis associated with infectious etiologies 3,4 . They have also been used in the management of hemoptysis in the setting of malignancy 5 . Furthermore, they have been effective in the management of life-threatening hemoptysis 3 .…”

“…The exact mechanism by which EBV cease active bleeding remains unclear. There are several proposed mechanisms for the clinical efficacy of EBV in the management of hemoptysis 5 . First, EBV may physically impede bleeding.…”