Endocan and Erectile Dysfunction

Balta, Şevket; Mikhailidis, Dimitri P.

doi:10.1177/1557988319893889

Cited by 6 publications

(8 citation statements)

References 14 publications

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Section: C-reactive Protein-albumin Ratio and Erectile Dysfunctionmentioning

confidence: 99%

“…Erectile dysfunction (ED) is associated with risk factors resulting in endothelial dysfunction (Balta & Mikhailidis, 2019). Inflammation markers may contribute to the pathogenesis of ED (Balta & Mikhailidis, 2019). Higher C-reactive protein (CRP) and lower albumin levels are indicators of inflammation and are associated with inflammatory disease (Balta et al, 2014;Sheikh et al, 2015).…”

Section: C-reactive Protein-albumin Ratio and Erectile Dysfunctionmentioning

confidence: 99%

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C‐reactive protein–albumin ratio and erectile dysfunction

Balta

Mikhailidis

2022

Andrologia

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Section: C-reactive Protein-albumin Ratio and Erectile Dysfunctionmentioning

confidence: 99%

Section: C-reactive Protein-albumin Ratio and Erectile Dysfunctionmentioning

confidence: 99%

C‐reactive protein–albumin ratio and erectile dysfunction

Balta

Mikhailidis

2022

Andrologia

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“…Erectile dysfunction is well known as a predictor of early atherosclerosis and is associated with the presence of vascular risk factors [27]. Increased endocan levels may represent the endothelial and inflammatory components of the pathogenesis of erectile dysfunction and may, therefore, prove useful in clinical practice [28].…”

Section: Endocan and Atherosclerosismentioning

confidence: 99%

Endocan: a new marker of endothelial function

Balta

Mikhailidis

2021

Current Opinion in Cardiology

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Purpose of reviewTo consider the role of endocan as an inflammatory marker in cardiovascular diseases. Recent findingsEndocan, an endothelial inflammatory marker, is associated with cardiovascular disease. SummaryVascular endothelial inflammation plays a key role in the pathogenesis of inflammatory and cardiovascular diseases by influencing thrombogenesis, tumour invasion and secretion of bioactive mediators. We discuss the role of endocan mainly in the context of cardiology.

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“…18 Increased levels were reported in cardiovascular diseases 19 and patients with erectile dysfunction. 20 Endocan is also a potential inflammatory marker and may reflect ED. 19,21 Endocan was shown to have predictive value on major adverse cardiovascular events after acute coronary syndrome.…”

Section: Testing Endothelial Functionmentioning

confidence: 99%

Endothelial Function in Patients With Continuous-Flow Left Ventricular Assist Devices

et al. 2020

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The endothelium plays a crucial role in maintaining cardiovascular homeostasis. Shear stress generated by flowing blood regulates the release of substances that provide adequate tissue perfusion. The extent of damage to endothelial cells depends on locally disturbed shear stress caused by the deteriorated flow. Patients with heart failure have reduced cardiac output, which results in reduced blood flow and negative shear stress. Reduced shear stress also affects microcirculation and reduces tissue perfusion. Consequently, the production of free oxygen radicals is increased and bioavailability of nitric oxide is additionally decreased. Therefore, endothelial dysfunction is involved in the progression of heart failure and cardiovascular events. Left ventricular assist devices (LVAD) are used for the treatment of patients with advanced heart failure. Older pulsatile flow LVADs were mostly substituted by continuous-flow LVADs (cf-LVADs). Despite the advantages of the cf-LVADs, the loss of pulsatility leads to different complications on the micro- and macrovascular levels. One of the pathogenetic mechanisms of cardiovascular complications with cf-LVADs may be endothelial dysfunction, which after the implantation of the device does not improve and may even deteriorate. In contrast, the pulsatile pattern of LVADs on blood flow could preserve endothelial function.

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Endocan and Erectile Dysfunction

Cited by 6 publications

References 14 publications

C‐reactive protein–albumin ratio and erectile dysfunction

C‐reactive protein–albumin ratio and erectile dysfunction

Endocan: a new marker of endothelial function

Endothelial Function in Patients With Continuous-Flow Left Ventricular Assist Devices

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