Endocardial Pacing in Infants and Young Children Weighing Less Than 10 Kilograms

Campos-Quintero, Aldo; García-Montes, José Antonio; Cruz-Arias, Rubén; Zabal-Cerdeira, Carlos; Calderón‐Colmenero, Juan; Sandoval, Juan Pablo

doi:10.1016/j.rec.2017.02.036

Cited by 5 publications

(7 citation statements)

References 5 publications

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“…Perera et al described a missense mutation (pGln181His) in 11 phenotypically affected family members with a strong family history of CHD, AV block, and SCD ( 7 ). Mutations in the NKX2-5 gene have also been reported in patients with dilated cardiomyopathy and LVNC ( 8 , 9 ). In a study by Yuan et al, dilated cardiomyopathy was documented in a family with a novel heterozygous NKX2-5 mutation (p.Ser146Trp).…”

Section: Discussionmentioning

confidence: 99%

Case Report: A Novel NKX2-5 Mutation in a Family With Congenital Heart Defects, Left Ventricular Non-compaction, Conduction Disease, and Sudden Cardiac Death

Morlanes-Gracia

Antoniutti

Alvarez-Rubio

et al. 2021

Front. Cardiovasc. Med.

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The NKX2-5 gene encodes for a transcription factor crucial for cardiac cell differentiation and proliferation. It was the first gene associated with congenital heart disease (CHD) in humans and has been linked to conduction disorders or cardiomyopathies. However, an overlapping phenotype is not frequent in the literature. We describe a family with a novel missense mutation in the NKX2-5 gene (p.Gln181Pro) with numerous antecedents with atrial septal defect (ASD), left ventricular non-compaction (LVNC), conduction disease, and sudden cardiac death (SCD).

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Section: Discussionmentioning

confidence: 99%

Case Report: A Novel NKX2-5 Mutation in a Family With Congenital Heart Defects, Left Ventricular Non-compaction, Conduction Disease, and Sudden Cardiac Death

Morlanes-Gracia

Antoniutti

Alvarez-Rubio

et al. 2021

Front. Cardiovasc. Med.

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“…Varios estudios han encontrado que es un factor de riesgo importante, asociado con peores resultados como mayor mortalidad, morbilidad y hospitalización prolongada (9) . Mientras tanto, la ferropenia también es frecuente en el preoperatorio de cirugía cardíaca de indicación electiva, y ha demostrado aumentar los requerimientos de transfusiones y la fatiga en el posoperatorio (1) .…”

Section: Valor Pronóstico De La Anemia Leve/moderada Y/o La Ferropenia Preoperatoria En El Posoperatorio De Cirugía Cardíacaunclassified

“…Palavras chave: marcapasso anticoagulação cirurgia cardíaca ecocardiograma angioplastia El implante de marcapaso en la población pediátrica es infrecuente, correspondiendo a menos de 1% de los implantes totales. Cuando es requerido, es más común en menores de 10 años, en relación con la población adulta cuya edad media es de 75,5 años (1) . Aunque en los pacientes pediátricos la experiencia en el uso de marcapasos es relativamente escasa, los múltiples avances en la cirugía cardíaca infantil han propiciado un aumento en el número de implantes de marcapaso.…”

Section: Introductionunclassified

Lo mejor del Congreso SUC 2021

2021

Rev.Urug.Cardiol.

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de Cardiología se llevó a cabo exclusivamente en modalidad virtual, del 26 al 28 de mayo. Contó con invitados nacionales e internacionales, permitiendo el desarrollo de un espacio de actualización en distintas áreas de la cardiología. Al igual que en años anteriores, se destinó un espacio a la actividad científica efectuada por investigadores nacionales mediante la presentación de temas libres. Durante 2020 se presentaron diversos trabajos en este formato que fueron sometidos a un proceso de revisión y aprobación por el comité científico, cuya presentación fue diferida por la pandemia por COVID-19. A continuación, comentamos algunos de los trabajos presentados en el congreso, a saber:• Implante primario de marcapaso definitivo cardíaco en población pediátrica y evolución: experiencia de 15 años en centro de referencia cardiológico pediátrico en Uruguay.• Calidad de la anticoagulación oral con warfarina en una policlínica de cardiología, seguimiento de un año.• Valor pronóstico de la anemia leve/moderada y/o la ferropenia preoperatoria en el posoperatorio de cirugía cardíaca.• Impacto pronóstico del ecocardiograma de estrés con ejercicio físico negativo en una unidad de dolor torácico. Período 2019-2020 con seguimiento a un año.• Estrategia invasivoconservadora en el infarto con elevación del ST. Prueba de concepto.• Impacto cardiovascular de la pandemia por COVID-19 durante el primer semestre de 2020 en Uruguay. Estudio ecológico.• Correlación entre parámetros hemodinámicos y captación de 18 F-fluoruro mediante PET a corto plazo luego de sustitución valvular aórtica.• Indicación, resultados y mortalidad de la angioplastia coronaria con implante de stent en tronco de arteria coronaria izquierda no protegido.

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“…22 However, successful pacemaker implantation has been reported even in small children weighing less than 10 kg. 23 This indicates that device therapy in this age category is extremely challenging, and a proper selection of devices and implantation technique is essential for improving the success rate and to preserve the functionality of the device on a longer term.…”

Section: Implantation Of Intracardiac Devices In Chd -A Challenging Pmentioning

confidence: 99%

“…30 This mismatch could determine lead displacement requiring reintervention and placement of a new, longer lead. 23 Subcutaneous implantable devices could avoid this risk of lead mismatch and represent a promising alternative to traditional ICDs, especially in pediatric patients.…”

Section: Subcutaneous and Leadless Implantable Devices In Childrenmentioning

confidence: 99%

Modern Technology for Prevention of Sudden Cardiac Death – a Clinical Update on Device Therapy in Children with Congenital Heart Diseases

Casu

2018

Journal of Cardiovascular Emergencies

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Sudden cardiac death in children is one of the most devastating conditions that can be encountered in acute cardiac care. Intracardiac device therapy, providing prompt and effective treatment in malignant ventricular arrhythmia or in severe conduction abnormalities, is a promising tool to reduce the incidence of this fatal condition. However, the implementation of device-based therapy in the pediatric population is currently limited by the lack of clinical studies on large number of subjects. As a result, indications for device therapy in pediatric patients are still unclear in many circumstances. There are also several particularities related to device implantation in pediatric age, such as the somatic growth leading to a mismatch between chamber size and lead length, or the difficulties of implantation technique in children with small body weight. This study aims to present an update on the current advantages and limitations of device-based therapy for treating severe malignant arrhythmia or conduction disorders in children at risk for sudden cardiac death.

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Endocardial Pacing in Infants and Young Children Weighing Less Than 10 Kilograms

Cited by 5 publications

References 5 publications

Case Report: A Novel NKX2-5 Mutation in a Family With Congenital Heart Defects, Left Ventricular Non-compaction, Conduction Disease, and Sudden Cardiac Death

Case Report: A Novel NKX2-5 Mutation in a Family With Congenital Heart Defects, Left Ventricular Non-compaction, Conduction Disease, and Sudden Cardiac Death

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Modern Technology for Prevention of Sudden Cardiac Death – a Clinical Update on Device Therapy in Children with Congenital Heart Diseases

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