Endocardite infectieuse : caractéristiques cliniques et pronostic entre 2004 et 2014 dans un hôpital non universitaire

Capilla, E.; Poyet, Raphaël; Tortat, A.V.; Marchi, Joisy Aparecida; Brocq, F.-X.; Pons, Frédéric; Kerebel, Sébastien; Jégo, C.; Mayet, Aurélie; Cellarier, Gilles

doi:10.1016/j.ancard.2016.09.042

Cited by 4 publications

(11 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This finding is different from other studies, which have shown that S. viridans is the most common pathogenic organism. (Jean et al, 2017;Kuijpers et al, 2017), However, our findings are consistent with those of more recent studies (Capilla et al, 2017;Marks, et al, 2015). which have shown an increasing predominance of staphylococcal infection in some regions of the world.…”

Section: Discussionsupporting

confidence: 93%

“…One of the main reasons for the difficulty in the treatment of IE is that the affected patients generally have severe pre-existing diseases and their general condition may already be poor 3. In a recent study, Capilla et al (2017) showed that IE continues to remain a serious condition and that S. aureus is the most common pathogenic organism involved in IE Capilla et al (2017).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Descriptive Epidemiological, Clinical and Microbiological Features of Infective Endocarditis at a University Hospital in Saudi Arabia

Kaki

Al-Abdullah

2018

American Journal of Infectious Diseases

View full text Add to dashboard Cite

Infective Endocarditis (IE) still remains a serious disease. The treatment and pathology still remain unclear. In this study, we sought to clarify the epidemiology and treatment of IE in a teaching hospital in Saudi Arabia. In this study, we sought to conduct a retrospective investigation of all adult patients who were treated for IE at our hospital and determine the characteristic demographic, clinical and pathological features. Our findings indicate that the main risk factors of IE were surgical intervention (28%) and structural heart disease (20%). The mean (SD) age of the patients in our study was 48 (18). The most common organisms identified were Staphylococcus aureus (40%) and Streptococcus viridans (30%). The most common clinical presentations were anorexia, weight loss and shortness of breath. IE was accompanied by valvular dysfunction in most cases (83%) and vegetation (55%). About 83% of the patients had undergone transthoracic echocardiography. Our findings provided some insight into the current trends in the epidemiology and clinical features of IE in Saudi Arabia.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Descriptive Epidemiological, Clinical and Microbiological Features of Infective Endocarditis at a University Hospital in Saudi Arabia

Kaki

Al-Abdullah

2018

American Journal of Infectious Diseases

View full text Add to dashboard Cite

show abstract

“…In this work the hospital prevalence of infectious endocarditis was 1.3%. Patients with AE are young in Africa, while they are older in western series (mean age 30 vs 60-70) [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20]. Clinical signs were dominated by the combination of fever + heart murmur.…”

Section: Discussionmentioning

confidence: 99%

“…Indeed, in our study, 77.8% of patients had already taken antibiotics before arriving in cardiology, either on self-medication, or on unwanted medical prescription. However, in the Western series, previous antibiotic therapy is observed only around 20% of cases [2,7,8,11,12].…”

Section: Discussionmentioning

confidence: 99%

“…Infectious endocarditis (AE) remains a serious disease, with an overall mortality of 20 to 30% in the West, despite advances in antibiotic therapy and surgery heart rate [1][2][3][4][5][6][7][8][9][10][11][12][13]. In sub-Saharan Africa, the low socioeconomic level of patients, cultural context, diagnostic delay, antibiotic limits and difficult accessibility of cardiac surgery, make the prognosis of AE quite reserved with significantly higher mortality than in the West [14][15][16][17][18][19][20].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Infectious Endocarditis in Sub-Saharan Africa: Epidemic-Clinical Aspects, Evolutionary and Prognostic: Multicentre Study on 81 Cases Followed Over 1 Year in Lomé (Togo)

Baragou¹,

Pessinaba²,

Simwetare³

et al. 2020

JICOA

View full text Add to dashboard Cite

Introduction: Infectious endocarditis remains a relatively common, serious pathology and suffering heavy mortality in sub-Saharan Africa. Purpose: The objective of this study was to describe the epidemic-clinical, evolutionary aspects patients hospitalized for infectious endocarditis and assess their prognosis. Methods: This is a prospective, 5-year, multicentre study of 81 hospitalized patients and treated for infectious endocarditis. These patients were followed for at least a year. Results: We observed that in our sub-Saharan context, patients who suffer from infectious endocarditis are often young, with an average age of 30 years. Rheumatic valve disease and congenital heart disease underlying the most frequent. Blood cultures are often negative, making it difficult the choice of appropriate antibiotic therapy. Surgical treatment (heart surgery) is difficult to access (2% in our study). As a result, the mortality is very high (63% at 1 year), with a survival rate of only 37% at 1 year. Conclusion: Our study shows that despite progress in diagnosis and therapeutic management, infectious endocarditis remains a pathology serious with heavy mortality in sub-Saharan Africa. It is important to highlight the importance of prevention, early diagnosis of infectious endocarditis, and especially the need for early medical-surgical management of these patients to improve their prognosis.

show abstract

Clinical and Microbiological Characteristics of Infective Endocarditis at a Cardiac Center in Saudi Arabia

Barry

Bari

Akhtar

et al. 2021

J Epidemiol Glob Health

View full text Add to dashboard Cite

Background Infective endocarditis (IE) is a serious disease with complex pathology and significant mortality. Little information is known regarding clinical and microbiological characteristics in Saudi Arabia. This study surveyed these characteristics at a Cardiac Center in Riyadh, Saudi Arabia over a period of 5 years. Methods This retrospective study was done on all infective endocarditis (IE) patients admitted to Prince Sultan Cardiac Center between January 1, 2015, and December 31, 2019. Clinical characteristics, microbiological results, management, and outcomes were assessed. Result A total of 340 cases of infective endocarditis were identified over the study period. Most patients (64%) were 50 years old or above, and 67% were males. Fever was the most common clinical presentation, and a murmur was audible in a fifth of patients. Blood cultures were positive in 177 (52%) cases. The most common organisms were Staphylococcus aureus, coagulase negative Staphylococcus and viridans group Streptococcus. Most common microbiological organisms causing native valve endocarditis were viridans group Streptococcus (32%) followed by methicillin-susceptible Staphylococcus aureus (21%), and for prosthetic valve endocarditis they were coagulase negative Staphylococcus (32%) followed by methicillin-susceptible Staphylococcus aureus (23%), the most common causes of culture negative endocarditis were Q-fever and brucellosis. Predisposing cardiac conditions were present in 127 (37%) patients, most commonly rheumatic heart disease and congenital heart disease. Surgical intervention was done in 26% of cases, with an overall in-hospital mortality rate of 6.76%. Conclusion We demonstrate the epidemiological, clinical, and microbiological profile of infective endocarditis in a tertiary care cardiac center in Saudi Arabia. It gives information concerning the prevalence of responsible organisms. This information will be helpful in assessing patients with suspected IE and in planning management of cases knowing the relative frequency of types of microorganisms encountered.

show abstract

Endocardite infectieuse : caractéristiques cliniques et pronostic entre 2004 et 2014 dans un hôpital non universitaire

Cited by 4 publications

References 16 publications

Descriptive Epidemiological, Clinical and Microbiological Features of Infective Endocarditis at a University Hospital in Saudi Arabia

Descriptive Epidemiological, Clinical and Microbiological Features of Infective Endocarditis at a University Hospital in Saudi Arabia

Infectious Endocarditis in Sub-Saharan Africa: Epidemic-Clinical Aspects, Evolutionary and Prognostic: Multicentre Study on 81 Cases Followed Over 1 Year in Lomé (Togo)

Clinical and Microbiological Characteristics of Infective Endocarditis at a Cardiac Center in Saudi Arabia

Contact Info

Product

Resources

About