Endocrine and metabolic physiology

Geor, Raymond J.

doi:10.1016/b978-0-7020-3422-0.00002-x

Cited by 3 publications

(3 citation statements)

References 249 publications

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“…It is recommended for horses and ponies with insulin resistance to be offered feed with less than 10% to 12% NSC (which includes simple sugars, fructans, and starches) of dry matter (Geor, 2010(Geor, , 2013. The horses in this study were offered feed with the NSC lower (4.5 to 8%) than this recommendation, whereas the ponies had higher NSC content (12.9 to 19.9%).…”

Section: Influences Of the Non-structural Carbohydrate Content In The Pasturesmentioning

confidence: 89%

Circulating microRNAs in insulin resistant horses and ponies

et al. 2021

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Insulin resistance is a prevalent disorder among horses and is associated with abnormal adiposity, laminitis, equine metabolic syndrome, and pituitary pars intermedia dysfunction. The processes leading to equine insulin resistance and associated conditions remain subject for study. MicroRNAs (miRNAs) are involved in regulation of many biological processes and diseases. The current study aimed to investigate the circulating miRNA profile of insulin resistant horses and ponies. It was hypothesized that insulin resistant horses would have a different circulating miRNA profile compared to healthy ones. 12 Thoroughbred/ Thoroughbred-cross and 12 Welsh/Dartmoor non-pregnant mares were evaluated for insulin sensitivity using frequent sampling intravenous glucose tolerance test (FSIGTT). Serum samples were collected for miRNA profiling through RT-qPCR analysis. Horses and ponies were divided into insulin sensitive (IS) or insulin resistant (IR) groups and their miRNA profiles compared. Results demonstrated that 13 miRNAs were differently expressed between IR and IS horses, 15 between IR and IS ponies, 17 between horses and ponies, and 10 between IR and IS animals (horses and ponies combined) (p<0.05). Finally, 8 miRNAs were proposed as potential regulators of equine insulin resistance. miRNA profiling is a potential tool to evaluate insulin resistance and associated conditions.

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Section: Influences Of the Non-structural Carbohydrate Content In The Pasturesmentioning

confidence: 89%

Circulating microRNAs in insulin resistant horses and ponies

et al. 2021

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“…Butyrate is key in supporting intestinal cell health whereas acetate and propionate are energy precursors (Geor 2013). The intensity of these processes depends on the amount and temporal influx of fermentable material arriving from the small intestine (Hintz et al 1971;Argenzio et al 1974;Glinsky et al 1976;Clarke et al 1988;Merritt and Julliand 2013).…”

Section: Hindgutmentioning

confidence: 99%

“…Ingestion of excessive levels of starch may exceed the relatively limited amylolytic capacity of the equine foregut and the undigested starch, together with any resistant starch, will pass into the large intestine where it will be fermented, yielding less net energy than if absorbed as glucose (Geor ). Several studies have reported decreased caecal and/or colonic pH in horses or ponies fed high starch diets (e.g.…”

Section: Basic Principles Of Gastrointestinal Physiology As It Influementioning

confidence: 99%

Nutritional tips for veterinarians

Harris¹,

Dunnett²

2016

Equine Veterinary Education

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Summary As a herd‐living, nonruminant, hindgut fermenting, primarily grazing herbivore the horse has evolved with a specialised gastrointestinal tract capable of utilising a wide range of plant species, which are hydrolysed and/or fermented to yield energy and nutrients for bodily processes. Domestication has resulted in the horse often being fed and managed to suit human requirements rather than their own, which can lead to digestive, behavioural and clinical issues. Appropriate nutrition not only reduces the risk of a nutritional component being a limiting factor to performance, but it also supports the maintenance of health and appropriate behaviour. A basic understanding of the digestive processes therefore can be very valuable when deciding how to feed horses optimally for both health and activity. This article provides a general overview of the gastrointestinal tract from a nutritional perspective and points out a few key practical areas where knowledge of feeding practices can be helpful for veterinarians.

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Nutrition for the equine athlete

Harris

Geor²

2014

Equine Sports Medicine and Surgery

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Endocrine and metabolic physiology

Cited by 3 publications

References 249 publications

Circulating microRNAs in insulin resistant horses and ponies

Circulating microRNAs in insulin resistant horses and ponies

Nutritional tips for veterinarians

Nutrition for the equine athlete

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