Endocrine changes associated with the human aging process: II. Effect of age on the number and size of thyrotropin immunoreactive cells in the human pituitary
“…The effect of aging on peripheral responsiveness to thyroid hormones in humans remains a matter of speculation. The increased prevalence of primary hypothyroidism is also a more plausible explanation for the thyrotrope hypertrophy and relative hyperplasia observed in one immunohistochemical study (179). Hypothalamic-pituitary control of thyroid function.…”
Section: Serum Thyroid Hormone Concentration and Transportmentioning
“…The effect of aging on peripheral responsiveness to thyroid hormones in humans remains a matter of speculation. The increased prevalence of primary hypothyroidism is also a more plausible explanation for the thyrotrope hypertrophy and relative hyperplasia observed in one immunohistochemical study (179). Hypothalamic-pituitary control of thyroid function.…”
Section: Serum Thyroid Hormone Concentration and Transportmentioning
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