Endocrine Disorders that Cause Diabetes

Jennings, Rachel; Hanley, Neil A.

doi:10.1002/9781118924853.ch20

Cited by 4 publications

(9 citation statements)

References 134 publications

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“…Our patient underwent bilateral adrenalectomy, subsequently achieving diabetes remission one year after surgery. These results can also occur after successful treatment of secondary diabetes in other endocrinopathies, such as Cushing's syndrome and acromegaly (11).…”

Section: Discussionmentioning

confidence: 98%

“…Lipolysis in adipose tissue is also stimulated via the β1and β3-adrenoceptors. In addition, epinephrine can impair glucose utilization in muscle through direct β2-adrenergic effects (11).…”

Section: Discussionmentioning

confidence: 99%

“…The prevalence of diabetes in patients with endocrinopathies varies from 33% to 50%. 1 , 11 However, diabetes secondary to endocrine disorders is very rare and constitutes less than 0.3% of diabetes cases worldwide. 12 The pathophysiology of impaired glucose tolerance in pheochromocytoma is multifactorial.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, epinephrine can impair glucose utilization in the muscle through direct β2-adrenergic effects. 11 …”

Section: Discussionmentioning

confidence: 99%

“…These results can also occur after successful treatment of secondary diabetes in other endocrinopathies, such as Cushing's syndrome and acromegaly. 11 …”

Section: Discussionmentioning

confidence: 99%

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Surgical Remission of Diabetes in a Patient With Mutation of RET Proto-Oncogene

Concepción-Zavaleta

Flórez

Moya

et al. 2021

AACE Clinical Case Reports

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…In addition, epinephrine can impair glucose utilization in the muscle through direct β2-adrenergic effects. 11 …”

Section: Discussionmentioning

confidence: 99%

“…These results can also occur after successful treatment of secondary diabetes in other endocrinopathies, such as Cushing's syndrome and acromegaly. 11 …”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Surgical Remission of Diabetes in a Patient With Mutation of RET Proto-Oncogene

Concepción-Zavaleta

Flórez

Moya

et al. 2021

AACE Clinical Case Reports

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Longitudinal changes in blood biomarkers and their ability to predict type 2 diabetes mellitus—The Tromsø study

Allaoui

Rylander

Averina

et al. 2022

Endocrino Diabet & Metabol

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Introduction Identification of individuals at high risk of developing type 2 diabetes mellitus (T2DM) is important for early prevention of the disease. Once T2DM is established, it is difficult to treat and is associated with cardiovascular complications and increased mortality. We aimed to describe pre‐ and post‐diagnostic changes in blood biomarker concentrations over 30 years in individuals with and without T2DM, and to determine the predictive potential of pre‐diagnostic blood biomarkers. Methods This nested case–control study included 234 participants in the Tromsø Study who gave blood samples at five time points between 1986 and 2016: 130 did not develop T2DM and were used as controls; 104 developed T2DM after the third time point and were included as cases. After stratifying by sex, we investigated changes in pre‐ and post‐diagnostic concentrations of lipids, thyroid hormones, HbA1c, glucose and gamma‐glutamyltransferase (GGT) using linear mixed models. We used logistic regression models and area under the receiver operating characteristic curve (AROC) to assess associations between blood biomarker concentrations and T2DM, as well as the predictive ability of blood biomarkers. Results Cases and controls experienced different longitudinal changes in lipids, free T3, HbA1c, glucose, and GGT. The combination of selected blood biomarker concentrations and basic clinical information displayed excellent (AROC 0.78–0.95) predictive ability at all pre‐diagnostic time points. A prediction model that included HDL (for women), HbA1c, GGT, and basic clinical information demonstrated the strongest discrimination 7 years before diagnosis (AROC 0.95 for women, 0.85 for men). Conclusion There were clear differences in blood biomarker concentrations between cases and controls throughout the study, and several blood biomarkers were associated with T2DM. Selected blood biomarkers (lipids, HbA1c, GGT) in combination with BMI, physical activity, elevated blood pressure, and family history of T2DM had excellent predictive ability 1–7 years before T2DM diagnosis and acceptable predictive ability up to 15 years before diagnosis.

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Overview of diabetes and its curative approach using medicinal plants: A narrative review

Asogwa¹,

Ugwu²,

Ali³

2023

GSC Adv. Res. Rev.

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Diabetes mellitus is a long term, diverse metabolic illness with a complex pathophysiology. Hyperglycemia, which stems from anomalies in either insulin secretion or insulin action or both, is its defining feature. Metabolic dysfunctions involving proteins, carbohydrates, and fats originate from hyperglycemia, which can express itself in a variety of ways. The main cause of diabetes related morbidity and mortality is long term hyperglycemia, which frequently results in a variety of microvascular and macro vascular diabetic complications. The main biomarker for determining diabetes diagnosis is hyperglycemia. The increase in prevalence rate, high expense of treatment, common side effects of oral antidiabetic medications is a global health challenge. Therefore, medicinal plants could be a viable ways to maximize its utilization in both food and medicine for management of diabetes and its complications. This review discussed the classification of diabetes, its pathophysiology, approved drugs and several medicinal plants that are used to manage diabetes.

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Endocrine Disorders that Cause Diabetes

Cited by 4 publications

References 134 publications

Surgical Remission of Diabetes in a Patient With Mutation of RET Proto-Oncogene

Surgical Remission of Diabetes in a Patient With Mutation of RET Proto-Oncogene

Longitudinal changes in blood biomarkers and their ability to predict type 2 diabetes mellitus—The Tromsø study

Overview of diabetes and its curative approach using medicinal plants: A narrative review

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